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1)  PI 3 kinase
PI-3激酶
2)  PI4-kinase
PI(4)-激酶
3)  Janus kinase 3
Janus激酶3
1.
Objective To study the effects of hypoxia on the expression of interleukin-6(IL-6),interleukin-1β(IL-1β),receptor tyrosine kinase(RTK) and Janus kinase 3(JAK3) in pulmonary microvascular endothelial cells(PMVECs),and the regulatory effects of the co-cultured pulmonary arterial smooth muscle cells(PASMCs).
目的研究低氧对肺微血管内皮细胞(PMVECs)的白细胞介素(IL)6、IL-1β、受体酪氨酸激酶(RTK)和Janus激酶3(JAK3)表达的影响,以及肺动脉平滑肌细胞(PASMCs)在其中的调控作用。
4)  calpain3
钙激活酶3
1.
Studies on the Quality of Calpain3 and Its Function During Adeing Time;
钙激活酶3的性质及其在牛肉成熟过程中作用的研究
5)  mitogen activated protein kinase kinasse3/6(MKK3/6)
MAPK激酶3/6
1.
Aim To investigate the effects of valsartan on the expression of TGF-β1 mRNA and the activation of p38 mitogen-activated protein kinase(p38MAPK),mitogen activated protein kinase kinasse3/6(MKK3/6)and cAMP response element-binding protein1(CREB1) in glomerular mesangial cells under high concentration of glucose.
目的探讨高糖状态下肾小球系膜细胞中p38丝裂原活化蛋白激酶(p38 MAPK)、其上游因子MAPK激酶3/6(MKK3/6)和下游因子cAMP反应元件结合蛋白1(CREB1)的表达以及血管紧张素受体1拮抗剂(AT1Ra)缬沙坦的影响。
6)  GSK-3
糖原合酶激酶-3
1.
Results The activity of GSK-3 was stimulated(P<0.
方法用链脲佐菌素(streptozotocin,STZ)建立DM大鼠模型,用32P放射性配体结合实验检测各组糖原合酶激酶-3(glycogen synthase kinase-3,GSK-3)的活性。
2.
Many possible mechanisms of the formation of NFT had been suggested, but recently glycogen synthase kinase-3 (GSK-3) and its role in AD was extensively studied.
近年来糖原合酶激酶-3(glycogen synthase kinase-3,GSK-3)在AD发病中的作用受到了广泛重视,人们并对此作了大量的研究。
补充资料:1-Benzyl-4-hydroxy-4-(3-trifluorotolyl)pi-peridine
分子式:C19H20F3NO
分子量:335.37
CAS号:56108-27-1

性质:结晶。熔点 229-232.5℃。

制备方法:用苄基胺与丙烯酸甲酯在回流下加成,生成N,N-双(β-丙酸甲酯)苄胺,然后在甲醇钠作用下环合并转化成盐酸盐,得1-苄基-3-甲氧羰基-4-哌啶酮盐酸盐,将后者以盐酸水解并脱羧得1-苄基-4-哌啶酮,进而与间溴三氟甲苯、金属镁(格氏试剂)反应,得1-苄基-4-羟基-4-(3-三氟甲苯基)哌啶溴化镁,最后以盐酸水解制得该品。

用途:三氟哌丁苯盐酸盐的中间体。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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