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1)  tryptophanyl tRNA synthetase
色氨酰tRNA合成酶
2)  TrpRS
色氨酰-tRNA合成酶
1.
Diversities occurred between TrpRS or tRNATrp from different origins during evolution.
本文着眼于原核(枯草杆菌)和真核(人)来源的两种色氨酰-tRNA合成酶(tryptophanyl-tRNA synthetase,TrpRS)存在种属差异的区段,研究它们结构和功能的关系。
3)  human tryptophanyl-tRNA synthetase
人色氨酰tRNA合成酶
1.
In vitro transcripts of these mutant genes were tryptophanylated by Bacillus subtilis and human tryptophanyl-tRNA synthetases(TrpRS),and the kinetic parameters were determined.
subtilis)和人色氨酰tRNA合成酶(TrpRS)进行氨酰化反应,并测定动力学常数。
4)  tyrosyl-tRNA synthetase
酪氨酰-tRNA合成酶
1.
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively.
近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪氨酰-tRNA合成酶、甘氨酰-tRNA合成酶和丙氨酰-tRNA合成酶上的突变,可分别导致DI腓骨肌萎缩症(Charcot-Marie-Toothdisease,CMT)C型,腓骨肌萎缩症2D型及小脑浦肯雅(Purkinje)细胞丢失。
5)  glycyl-tRNA synthetase
甘氨酰-tRNA合成酶
1.
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively.
近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪氨酰-tRNA合成酶、甘氨酰-tRNA合成酶和丙氨酰-tRNA合成酶上的突变,可分别导致DI腓骨肌萎缩症(Charcot-Marie-Toothdisease,CMT)C型,腓骨肌萎缩症2D型及小脑浦肯雅(Purkinje)细胞丢失。
6)  alanyl-tRNA synthetase
丙氨酰-tRNA合成酶
1.
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively.
近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪氨酰-tRNA合成酶、甘氨酰-tRNA合成酶和丙氨酰-tRNA合成酶上的突变,可分别导致DI腓骨肌萎缩症(Charcot-Marie-Toothdisease,CMT)C型,腓骨肌萎缩症2D型及小脑浦肯雅(Purkinje)细胞丢失。
补充资料:氨基酰合成酶或氨基酰-tRNA合成酶


氨基酰合成酶或氨基酰-tRNA合成酶


  催化一个特定氨基酸与ATP形成AA-AMP,并使AA-AMP与特定的tRNA相结合形成AA-tRNA和游离AMP的酶,已发现20余种。
  
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