The application of peptidomimetics and virtual combinatorial peptide library in the computer-aided polypeptide design are brielfly described.

The peptidomimetics in drug design has been reviewed in the paper.

Preliminary study on biological function of mimic peptides of Treponema Pallidum screened from phage peptide library;

Preliminary screening mimic peptides of lipopolysaccharide binding protein binding to CD14;

Construction of the eukaryotic expression vector of duck HBV polymerase binding mimic peptide;

Construction and expression of 4 repeats of EPO mimetic peptide gene;

AIM: To obtain bioactive ICAM-1-mimetic peptide.

Expression and characteristic of the peptide mimics of blood group A antigen;

Peptide mimic of blood group A antigen:construction of the expression vector and determination of the mimicking ability;

Preparation of Polyclonal Anti-E. coli LPS Antibodies and Screening of Mimotopes of LPS from Liner 12-mer Phage Displayed Peptide Library;

To screen and identify the mimotopes for lipopolysaccharide(LPS) epitope, a random phage displayed dodecapeptide library was screened with a monoclonal antibody 2B4 specifically against LPS conservative epitope.

In the present study,the peptide phage display technique was applied to generate mimotope of the conserved neutralizing epitope recognized by 8H5 mAb.