1) antifungal spectrum
抗真菌谱
1.
The antifungal spectrum and stability of fermentation broth of the strain Streptomyces tz92 were studied.
研究了链霉菌Streptomyces tz92发酵液的抗真菌谱及稳定性。
2) antifungal agent
抗真菌药
1.
Advances in research of echinocandins drugs as antifungal agents;
棘白霉素类抗真菌药的研究进展
2.
Trichophyton rubrum: relationship between susceptibilities to antifungal agents and species specificities;
红色毛癣菌对抗真菌药物的敏感性与种株特异性的关系
3.
Flutrimazole, an antifungal agent, was synthesized from o-fluorobenzoyl chloride via Friedel-Crafts reaction with benzene, Grignard reaction with p-bromofluorobenzene, sulfonylation with methanesulfonyl chloride and then substitution with imidazole in 59% overall yield.
邻氟苯甲酰氯与苯经付-克反应、与对溴氟苯发生格氏反应、甲磺酰氯磺酰化,最后与咪唑发生取代反应制得抗真菌药氟曲马唑,总收率59%。
3) antifungal
抗真菌
1.
Recent advances in the study of antifungal lead compounds with new chemical scaffolds;
新结构类型抗真菌先导化合物的研究进展
2.
N-Myristoyltransferase: a novel antifungal target;
N-肉豆蔻酰基转移酶——抗真菌药物作用新靶点
3.
Study on antifungal action of twenty-two marine natural products;
22种海洋生物成分的体外抗真菌作用
4) antifungi
抗真菌
1.
Many researchs have focused on the screening the compounds for fungi s antitumaous effect, immunity improvement, while limited reports on the components with antibacterial and antifungi activities.
但是对其抗真菌、抗细菌的活性研究并不多。
2.
STUDIES ONTHE ACTIVE SECONDARYMETABOLITES OF SOIL FUNGIGraduator: Zhang YiSpecial field: MedicinaI chemistryTutor: Pei YuehuABSTRACTA bioassay through detecting deformation or groWth inhibition ofmycelia geminated from conidia of Pyricularia oIyZae, a plant pathogeincfungUs was efficiently applied fOr the primary screeinng of antitUmor andantifungi agents from secondny metabolites of soil fungi.
本文利用以稻瘟霉分生孢子和菌丝体形态变化为指标的生物筛选模型，从土壤真菌代谢产物中筛选抗真菌、抗肿瘤活性化合物。
5) Antifungal drug
抗真菌药
1.
Effects of seven kinds of antifungal drugs on fungi isolated from keratomycotic;
七种抗真菌药对眼部真菌的抗菌作用
2.
Cost-effectiveness analysis of three kinds of antifungal drug for treatment of onychomycosis;
3种抗真菌药治疗甲真菌病的成本-效果比较
3.
Pharmacology and clinical evaluation of sertaconazole nitrate,a novel antifungal drug;
新型抗真菌药硝酸舍他康唑的药理作用及临床评价
6) antifungal peptide
抗真菌肽
1.
Antifungal activity and the immunogenicity of antifungal peptide Drosomycin and its isoforms from Drosophila melanogaster;
黑腹果蝇抗真菌肽Drosomycin同系物的免疫原性和抗真菌活性
2.
Soluble expression of the antifungal peptide genes,Drs and Drs-lC,of Drosophila melanogaster in the prokaryote and the detection of their antifungal activity;
黑腹果蝇抗真菌肽基因Drs和Drs-lC的原核可溶性表达及抗真菌活性测定
3.
The relationships between the structure and function of insect antibacterial peptides and antifungal peptides and molecular design;
昆虫抗菌肽和抗真菌肽结构与功能的关系及分子设计
参考词条
补充资料：抗真菌药和抗立克次氏体药
抗真菌药和抗立克次氏体药
Chemotherapeutics, Antimycotic and Antirickettsial
kans抗真菌药和抗立克次氏体药第9卷 O }}(1)CICH之一C一CHZCI一-~甲~~~~~叫~~一~~~(2)CHaC00H FB了IJ ︸胜、!尸以.纵扮!F(48) OH lCICH:一C一CHZCIN=，、 1，1 NH尸丫r，一一三之~、汗尸Na月，DMF F(49)(11) :HzN~3。:。您丫督自气丛立竺竺自护、-跳沪/、‘犷HCOH、屯/卜‘2 (51)(52) 。之丫⑧ 坐助OH(‘2，(53) HCI-~~，~~~~~~，..~ 一H20‘HCI(90)侧 月F C.\H一\l尸n下.C上z、丫F H C 一 N =‘ N 1.1七(47) 氟康哇口服吸收快而完全，半衰期长(22~32h)体内分布均匀，能很好的透过血脑屏障，并渗透到脑脊液内阳〕。口服100mg后，脑脊液平均浓度为血浆浓度的0.58一0.89倍。70%原药由肾脏排除。 大多数病人对氟康哇耐受良好哪〕。常见的副作用为头痛、恶心、疲劳、发热、浮肿、出疹、腹部不适及转氨酶升高。但发生率小于5环，极少数病人出现血小板减少，停药后即恢复。·2.8.烯丙胺类 1981年发现蔡替芬(haftifine)(s0)具有较高的广谱抗真菌活性。由于其优良的抗真菌活性，新颖的结构特点，很快引起了人们的重视，通过对其结构改造和抗菌活性的研究，发现了活性高、毒性低的衍生物特比禁芬(terbinafine)(‘oa)和丁禁芬(botenafine)(乐ob)。活性最大，最低抑菌浓度(Mlc)为。.01一0.2哆/ml，对申克氏抱子丝菌和曲霉属真菌次之，Mlc分别为0.8一1.5限/耐和0.8~12.5阳/而。禁替芬的体外抗皮肤真菌活性明显优于咪哇类抗真菌药，而与托蔡醋(发癣退)和灰黄霉素相似。 蔡替芬对真菌细胞超微结构有影响，还干扰真菌细胞的脂质代谢，故有杀菌作用。在作用机理上蔡替芬与氮哇类药物一样，都是抑制麦角幽醇的生物合成，但作用部位二者不同，禁替芬是角拨烯的环氧化酶的特异性抑制剂。通过抑制角鳖烯的环氧化，使角盆烯蓄积和麦角幽醉缺乏，使真菌细胞膜的组成和通透性发生改变，导致杀菌作用[5，〕。 蔡替芬是一个高效低毒的外用抗真菌药，其疗效与克霉哇、美康哇、益康哇等外用抗真菌药相似。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。