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1)  Hepatocarcinogenic Factor
肝癌变因素
2)  relevant risk factors of HCC
肝癌相关危险因素
1.
Methods: To the 88 cases from HCC high incidence families and 115 from control families, relevant risk factors of HCC were collected by the questionnaires in the high risk area of Guangxi, at the same time 10ml peripheral blood were collected ,then the infection rate of HBV in serum were tested and the polymorphisms of GSTM1 and GSTT1 in.
方法:在肝癌高发现场以11个肝癌高发家族(88例)和相对应的11个非癌对照家族(115例)成员为研究对象,用问卷调查的方法收集研究对象的肝癌相关危险因素,同时采集研究对象的外周血各10ml,检测其HBV的感染标志物,并采用多重PCR法测定所有成员血细胞中的谷胱苷肽转硫酶M1(GSTM1)及谷胱苷肽转硫酶T1(GSTT1)的基因型。
2.
Methods:To the 30 case HCC from Han nationality and 30 case HCC from Zhuang nationality and 15 case from control population of non hepatocellular carcinoma,the relevant risk factors of HCC were collected by epidemiological investigation including inquiring,family medical history,smoking history, drinking wine history,drinking .
同时按肿瘤流行病学调查方法,制定统一表格询问病史、家族史、吸烟史、饮酒史、饮水史等及检查HBsAg等,收集研究对象的肝癌相关危险因素。
3.
Methods: To the 88 cases from HCC high incidence families and 115 from control families, relevant risk factors of HCC were collected by the questionnaires in the high risk area of Guangxi, at the same time 10ml peripheral blood were collected ,then the infection rate of HBV in serum were tested and the polymorphisms of GSTM1 and GSTT1 in.
方法:在肝癌高发现场以11个肝癌高发家族(88例)和相对应的11个非癌对照家族(115例)成员为研究对象,用问卷调查的方法收集研究对象的肝癌相关危险因素,同时采集研究对象的外周血各 10ml,检测其HBV的感染标志物,并采用多重PCR法测定所有成员血细胞中的谷胱苷肽转硫酶M1(GSTM1)及谷胱苷肽转硫酶T1(GSTT1)的基因型。
3)  hepatocarcinogenesis
肝癌变
1.
Study on expression of mutant P53 protein and point mutation in exon 6 of p53 gene during hepatocarcinogenesis in rats;
大鼠肝癌变中p53点突变及其蛋白表达的研究
2.
Expression of some oncogenes and point mutation of c-Ha-ras1 during hepatocarcinogenesis in rats;
大鼠肝癌变过程中几种癌基因的原位表达及c-Ha-ras1点突变的研究
3.
Quantitative study on morphologic features and proliferative activity during DEN-induced hepatocarcinogenesis in rats;
DEN诱发大鼠肝癌变的病理形态与细胞增殖活性的定量研究
4)  precancerous lesion of liver
肝癌前病变
1.
Effect of Zhenggan Fang on rat liver function of aflatoxin B_1-induced precancerous lesion of liver;
正肝方对黄曲霉毒素B_1诱发的肝癌前病变大鼠肝功能的影响
2.
[Conclusion]ZGF can inhibit the number and size of AFB-1-induced positive GGT foci and positive GST-P foci,and ZGF has the function of preventing AFB-1-induced precancerous lesion of liver.
[结论]正肝方能减少AFB1诱发的大鼠癌前病变肝组织GGT和GST-P阳性灶的数量和大小,对AFB1诱发的肝癌前病变具有一定的预防作用。
5)  preneoplastic nodules
肝癌前病变
1.
we study the anti-tumor effect and its mechanisms of different concentration Camellia chrysantha(Hu)Tuyama and it s flower in the rat s liver preneoplastic nodules induced by DEN.
一、目的: 根据广西肿瘤防治研究所病理研究室80年代已成功建立的AFB1致大鼠肝癌前病变短期体内实验动物模型,探索用二乙基亚硝胺(DEN)致大鼠肝癌前病变的最佳剂量;观察金花茶(Camellia chrysantha,CCT)茶花及不同浓度的金花茶浓缩液对DEN诱发大鼠肝癌前病变的作用。
6)  hepatic precancerous lesion
肝癌前病变
1.
Expression of Notch1、Delta、 NF-κB in rats hepatic precancerous lesion and the regulating effection of the Qinggan Huayu Formula;
Notch1、Delta、NF-κB在肝癌前病变大鼠中的表达及清肝化瘀方药的调节作用
补充资料:非密度制约因素(见密度制约因素)


非密度制约因素(见密度制约因素)


  l焦非密度制约因素见生态因素、密度制约后
  
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