Malignant transformation occurs during malignant changes of cells and the process of tumor cells changing from low grade to high grade malignancy.

[ Methods] Reverse transcription-polymerase chain reaction( RT-PCR)was used to measure the expression of tankyrase mRNA in 16HBE and malignant transformed cells.

Objective Through finding and analising 470 cases of Malignant cell of pleural effusion,ascites and perieardial effusion in 2 240 cases from January,2002 to December,2003,to discuss the cytomorphological diagnostic value of routine dropsyexamination on the basis of cytomorphological analyses.