Effect of puerarin on L-type calcium channel in isolated rat ventricular myocytes;

Studies have showed that many molecules participate in dentin calcification, such as L type calcium channels, Ca-ATPase, Na+/Ca2+ exchangers and calcium binding proteins.

Aim: Establishing patch-clamp whole cell recording technique to observe the effects of acute and chronic stress on L-type calcium channels electrophysiological characters of rat ventricular myocytes , and to explore its its mechnisms and significance in stress-induced cardiomyocyte injury.

CACNA1S gene was the coding gene of α1 subunit of L-type calcium channel,its mutation would induce low-potassium periodic paralysis of human and high-temperature syndrom of pig.

Effects of polyclonal antibody to L type calcium channel α1 D subunit on human dentinogenesis;