Aim To investigate the role of T type calcium channel of spinal cord and supraspinal on the pain threthold of the rats following chronic constriction injury(CCI) of the sciatic nerve.

Objective:To compare the change of T type calcium channel activity between the detrusor overactivity (DO) and control rats, and explore its role in the pathogenesis of DO.

Research progress of T-type calcium channels and the related drugs;

Objective:By observing the effect of mibefradil administered intrathecally on the mechanical and heat hyperalgesia following chronic constriction injury(CCI)of the sciatic nerve in rats,this study evaluates the role of T-type calcium channel in nociceptive transmission at the spinal level.

Objective:To study the relationship between the varicocele and the expression of human T-type calcium channel gene alphalH,alphal G in sperm and to provide a new direction for the pathophysiological mechanism of varicocele,in order to find new ideas for the diagnosis and treatment of infertility caused by varicocele.

Aim: Establishing patch-clamp whole cell recording technique to observe the effects of acute and chronic stress on L-type calcium channels electrophysiological characters of rat ventricular myocytes , and to explore its its mechnisms and significance in stress-induced cardiomyocyte injury.

Effect of puerarin on L-type calcium channel in isolated rat ventricular myocytes;