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1)  MTX resistance
MTX耐药
1.
To explore the molecular genetic background related to the MTX resistance in the mouse MTX resistant cells,differential PCR was used to determine the amplification and overexpression of DHFR gene.
为探讨MTX耐药的小鼠细胞中与耐药机制形成有关的分子遗传学背景 ,应用差异PCR技术 ,检测了MTX耐药细胞中DHFR基因的扩增和过表达 ,并对c myc及p5 3基因状态与dhfr扩增之间的相关性进行了探讨。
2)  resistance to MTX
MTX耐药性
1.
In order to understand the relationship between the resistance to MTX and the transport protein superfamily of ATP-binding cassette, and to investigate the mechanism of resistance to MTX, the study detected the expressions of mdr1, mrp1, mrp2, mrp3, mrp5, mrp6 and abcg2 tha.
结果显示,与MTX耐药性相关的ABC转运蛋白超家族成员主要为多药耐药相关蛋白,其中mrp1和mrp5呈现高表达,并且,在MTX抗性细胞中,MRP5在mRNA及蛋白水平的表达均明显增强,提示其在MTX耐药机制中起重要作用,可能为潜在的药物作用靶点。
3)  Methotrexate [英][,meθə'trekseit]  [美][,mɛθə'trɛkset]
MTX
1.
The Application on Treatment of Ectopic Pregnancy with High Dosage of Mifepristone Plus Methotrexate;
大剂量米非司酮联合MTX在异位妊娠中的应用
2.
Study on the mechanism for treatment for rheumatoid arthritis with methotrexate;
氨甲喋呤(MTX)治疗类风湿性关节炎机制的研究
3.
Objective To discuss the effect of methotrexate(MTX) interventional treatment in unruptured tubal pregnancy under B ultrasound guidance.
目的探讨B超引导下氨甲喋呤(MTX)局部治疗未破裂型输卵管妊娠的疗效。
4)  Resistance [英][rɪ'zɪstəns]  [美][rɪ'zɪstəns]
耐药
1.
Detection of erm and msrA genes in staphylococci with resistance to erythromycin;
红霉素耐药葡萄球菌中erm和msrA基因检测
2.
Acinetobacter baumannii:Its Clinical Investigation and Resistance Analysis;
鲍氏不动杆菌的临床分布特征及耐药趋势分析
3.
Taxol resistance in ovarian cancer and its management;
卵巢癌中紫杉醇耐药机制与克服耐药策略的研究进展
5)  antibiotic resistance
耐药
1.
Analysis of the pathogens and antibiotic resistance in nosocomial urinary tract infections in departments of neurology and neurosurgery;
神经内外科院内泌尿道感染病原菌分布及耐药性比较
2.
Distribution and antibiotic resistance of pathogens in lower airways infection in intensive care units;
重症监护病房下呼吸道感染病原菌流行及耐药现状特点
3.
Objective To understands the nosogenetic germ and its antibiotic resistance for our hospital paitients with urinary tract infection for a period February.
目的了解我院2002年2月~2005年3月泌尿系感染病原菌的耐药状况,指导临床合理应用抗菌药物。
6)  Drug resistance
耐药
1.
Analysis of pathogen distribution change and drug resistance in low respiratory tract infection;
下呼吸道感染病原菌变迁及耐药状况分析
2.
Biochemistry and pharmacology of the human multidrug resistance gene product, ABCG2;
多药耐药蛋白ABCG2的生物化学和药理学(英文)
3.
Study of drug resistance in 78 treatment-naive HIV-1 subtype B infected cases;
78例未经抗病毒治疗的HIV-1 B亚型感染者耐药结果分析
补充资料:耐药


耐药


  见抗菌药物敏感试验。
  
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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