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1)  kinase do-maine receptor
酪胺酸激酶膜受体
1.
[Objective] To study the effects of low-intensity ultrasound (LIUS) on the proliferation of vascular endothelial cells (VEC) after exposure to irradiation and the expression of kinase do-maine receptor (KDR).
[目的]探索低强度超声波对辐射后血管内皮细胞增殖功能和酪胺酸激酶膜受体(KDR)表达的作用。
2)  Receptor tyrosine kinase
受体酪氨酸激酶
1.
Expression and its clinical significance of receptor tyrosine kinase EphB1 in gastric carcinoma
受体酪氨酸激酶EphB1在胃癌中的表达及其临床意义
2.
Mer is one member of Axl receptor tyrosine kinase family, and its ligand Gas6 can stimulate activity of Mer receptor tyrosine kinase after binding it, and then activate the downstream signal transduction pathway, Mer participates in cell inflammation, apoptosis, tumorigenesis, thrombosis and hemostasis.
Mer是Axl受体酪氨酸激酶家族中的一员,其受体Gas6和Mer结合后可以激活Mer的酪氨酸激酶活性,并激活下游信号传导途径,在细胞炎症、凋亡、血液肿瘤发生发展以及血栓于止血等方面发挥作用。
3.
FLT3,a member of receptor tyrosine kinase III family,is primarily expressed by hematopoietic cells and plays a significant role in hematopoiesis and leukemogenesis.
FMS-like Tyrosine Kinase 3(FLT3)是一种受体酪氨酸激酶,在造血干细胞、前体B细胞等的增殖、分化以及存活中具有重要作用。
3)  receptor tyrosine kinases
受体酪氨酸激酶
1.
Modulation of potassium channels by receptor tyrosine kinases:recent progress;
受体酪氨酸激酶调节钾离子通道功能的研究进展
2.
The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases have close connection with the initiation, progression and progn osis of various malignancies.
表皮生长因子受体 (EGFR)家族的受体酪氨酸激酶与多种恶性肿瘤的发生、发展及预后等密切相关。
4)  RTK
受体酪氨酸激酶
1.
Receptor tyrosine kinase (RTK) inhibitors targeting VEGF receptor is one of the most promising agents.
血管内皮细胞生长因子 (VEGF)是体内活性最强、专属性最高的促血管生成因子 ,故成为寻找血管生成抑制剂的重要靶点 ,其中靶向 VEGF受体酪氨酸激酶的抑制剂令人最为关注。
2.
Our study is aimed to investigate whether EphA3,which is a member of RTK family,can play a role in PCa progression and whether it can promote the transition of PCa from androgen dependent stage to androgen independent stage as well as the mechanism of its function.
本课题旨在阐明受体酪氨酸激酶家族分子EphA3能否在前列腺癌进展中发挥作用,能否促进前列腺癌从雄激素依赖向雄激素非依赖的转变,并探索其发挥作用的分子机制,为发现新的前列腺癌相关信号转导途径,发现新的药物靶标和诊断治疗方法奠定基础。
5)  tyrosine receptor kinase
酪氨酸受体激酶
6)  tyrosine kinase receptor A(Trk A)
酪氨酸激酶受体A
1.
Objective To explore the effects of the neonatal handling and the enriched environment on nerve growth factor(NGF)and its tyrosine kinase receptor A(Trk A)in the forehead cortex and hippocampus of neonatal rats.
目的探讨早期触摸和环境刺激对新生鼠额皮质、海马神经生长因子(nerve growth factor,NGF)及酪氨酸激酶受体A(tyrosine kinase receptor A,Trk A)的影响。
补充资料:3-羟基酪胺氢溴酸盐
分子式:C8H11NO2·HBr
分子量:234.10
CAS号:645-31-8

性质:鳞片状结晶。熔点218-220℃。

制备方法:由3-O-甲基多巴胺盐酸盐(见24653)水解得到。将3-O-甲基多巴胺盐酸盐、48%氢溴酸及盐酸加入反应锅,缓慢升温至产生的气泡消失后再回流2h。静置过夜,析出结晶,冷却,过滤,用盐酸洗涤滤饼,真空干燥,得成品。

用途:药物多巴胺的中间体。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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