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1)  death signaling transduction pathway
死亡信号转导通路
1.
Aim To explore the relations between anti-apoptotic role of dipfluzine (DIP) and the death signaling transduction pathway initiated by CD95 molecules, and the transcription factor involved in the transcription regulation of CD95 molecules in the hippocampal CA1 region after transient forebrain ischemia.
结论 双苯氟嗪通过抑制CD95分子启动的死亡信号转导通路发挥其抗脑缺血再灌注损伤作用;这一作用与转录因子NF κB无关。
2.
OBJECTIVE To investigate whether dipfluzine (Dip) plays an anti-apoptotic role in the hippocampal CA1 region after transient forebrain ischemia and the relationship between the anti-apoptotic role of DIP and the death signaling transduction pathway initiated by CD95 (Fas) molecules.
目的 研究L 型钙通道拮抗剂双苯氟嗪在大鼠全脑缺血再灌注后海马CA1区神经元中的抗凋亡作用及与CD95 (Fas)分子启动的死亡信号转导通路之间的关系。
2)  RISK pathway
RISK信号转导通路
1.
RISK pathway and cardiac protection of renal ischemic postconditioning;
RISK信号转导通路与肾缺血后处理的心肌保护作用
3)  Signal transduction
信号转导通路
1.
Akt is thought to be a key mediator of signal transduction processes,it plays important roles in regulating cell survival,growth,proliferation,function and nutrient metabolism in heart in response to growth factors and other extracellular stimuli.
关键词:Akt,心肌保护,信号转导通
4)  mitogen-activated protein kinase pathway
MAPK信号转导通路
1.
Objective To study the antitumor effect of toremifene on MCF7 cell lines,and investigate the role of mitogen-activated protein kinase pathway.
结论MAPK信号转导通路在TOR非雌激素抗肿瘤中发挥重要作用,MAPK通路抑制剂与TOR联合应用可发挥协同作用,增强其抗肿瘤效用。
5)  Signaling transduction pathway
信号转导通路
1.
AIM: To investigate the role of Wnt/β-catenin signaling transduction pathway in rat hepatocarcinogenesis.
目的:探讨Wnt/β-catenin信号转导通路与肿瘤发生的关系,为肝癌的防治提供新的思路。
2.
AIM To investigate the expressions of associated proteins of signaling transduction pathway in hippocampal nerve system of KKAy mouse with type 2 diabetes.
结论 2型糖尿病KKAy小鼠存在海马胰岛素信号转导通路的异常 ,主要表现为Ras途径和PI3 K两条途径的异常。
6)  signaling pathway
信号转导通路
1.
AIM: To explore the possible mechanism of action of Wnt/β-catenin signaling pathway in hepatocarcinogenesis by investigating the different expressions of the main members on this signaling pathway in hepatocellular carcinoma cell line HepG2 and L02 cell line.
目的:比较Wnt/β-catenin信号分子在HepG2和L02细胞中的表达,探讨Wnt/β-catenin信号转导通路在肝癌发生中的作用机制,为肝癌的防治提供新的思路。
2.
TLR4-mediated MyD88(myeloid differentiation protein 88 ) signaling pathway p
TLR4(Toll-like receptor 4,TLR4)是一种模式识别受体(patternrecognition receptor,PRRs),能识别病原体,在病原体入侵机体的早期启动固有免疫,TLR4介导的髓样分化蛋白MyD88(myeloid differentiation protein 88,MyD88)信号转导通路在抗感染中发挥重要作用。
补充资料:脉心导敏 ,脉导敏,英他佐明,麦新导明
药物名称:吗多明

英文名:Molsidomine

别名: 吗导敏;吗多明;吗斯酮胺;脉心导敏 ,脉导敏,英他佐明,麦新导明
外文名:Molsidomine
特点:
脉导敏是一种属于亚胺类化合物,其作用与硝酸盐相似。舌下含服1毫克,2~4分钟起作用,可阻止心绞痛发作。口服一次可持续6~7小时,剂量每天3次,每次2毫克。副作用包括头痛、头胀、脸部发热感等,但不多见。
适应症:
防治心绞痛的发作。
用量用法:
口服:1次1~2mg,1日2~3次,发作时舌下含服:1次2mg。喷雾吸入:每次揿吸1~2次(相当于本品0.2~0.4mg),每日次数酌定。
注意事项:
1.一般不良反应可有头痛、面部潮红、眩晕等,停药后可自行消失。 2.低血压、青光眼病人忌用。
规格: 片剂:每片1mg、2mg。 气雾剂:每瓶含42mg(可揿吸200次左右)。





类别:非选择性钙通道阻滞剂||防治心绞痛药
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条