1) ERK signal transduction pathway
ERK信号转导通路
1.
Objective By observing the changes in ultramicrostructures of synaptic, the expressions of synaptophysin, growth-associated protein-43 (GAP-43) and ERK protein by Aβ_ 1-40 -induced PC12 cells in vitro to investigate the possible mechanisms of ERK signal transduction pathway involved in Aβ_ 1-40 -induced nervous synaptic injury in Alzheimer’s disease (AD).
目的探讨ERK信号转导通路在β淀粉样蛋白1-40(Aβ1-40)诱导神经突触损伤中的可能作用机制。
2.
Objective: To investigate the expression of ERK signal transduction pathway and its significance in the cerebral cortex of rats after epileptic seizures.
目的:研究ERK信号转导通路在癫痫发病机制中的作用。
3.
Objective:To study the effect of ultramicrostructure of brain tissue and the ERK signal transduction pathway and neural stem cells proliferation and differentiation in brain ischemia rat treated with moxibustion at Ren meridians.
结论:艾灸任脉经穴治疗能改善局灶性脑缺血大鼠脑组织超微结构,艾灸任脉经穴能激活MCAO大鼠ERK信号转导通路,并能促进MCAO大鼠神经干细胞增殖与分化。
2) ERK pathway
ERK信号通路
1.
MEK1/2 are the key components of the ERK pathway.
基于细胞Raf/MEK/ERK信号通路与病毒复制的关系,应用Western印迹检测p-ERK1/2蛋白的表达、用终点滴定法测定病毒增殖量(TCID50),以及观察感染细胞的细胞病变效应(CPE)等,揭示单纯疱疹病毒Ⅱ型(HSV-2)复制与ERK通路的关系。
3) MER2/ERK SIGNAL TRANSOUCTION PATHWAY
MEK2/ERK信号传导通路
4) ERK-1/2 signaling pathway
ERK-1/2信号传导通路
5) Ras/Raf/MEK/ERK signal transduction
Ras/Raf/MEK/ERK信号传导通路
1.
Objective:To explore the Ras/Raf/MEK/ERK signal transduction mechanisms of Alzheimer\'s disease.
目的:探索Ras/Raf/MEK/ERK信号传导通路在阿尔茨海默病(Alzheimer\'s disease,AD)中的作用。
6) MAPK/ERK signal pathway
MAPK/ERK信号通路
1.
【Objective】To investigate the effects of Baicalin on proliferation inhibition and apoptosis induction in human chronic myeloid leukemia cell line K562 cells;on related proteins and mRNA expressions; and the role of PI3K/Akt、MAPK/ERK signal pathways in the apoptosis of K562 induced by Baicalin .
方法应用四甲基偶氮唑蓝(MTT)比色法绘制细胞生长曲线、克隆形成实验检测黄芩苷对K562细胞增殖的影响;AO/EB荧光染色、DNA片段化分析、AnnexinⅤ/PI细胞凋亡检测及TdT酶介导的末端缺失原位标记(TUNEL)法检测黄芩苷对K562细胞凋亡的影响;RT-PCR法检测黄芩苷作用前后K562细胞bcr/abl、c-myc、Bcl-2、Bax、h-tert基因mRNA表达的影响;蛋白印迹法(Western blotting)检测黄芩苷对K562细胞bcr/abl融合蛋白P210、磷酸化p210、c-myc、Bcl-2、procaspase-3、procaspase-9、PARP蛋白表达的影响及黄芩苷作用后K562细胞PI3K/Akt、MAPK/ERK信号通路蛋白表达水平的变化。
补充资料：上转
【上转】
（术语）本觉为化他而下向曰下转，始觉为自利而上进曰上转。又背本觉之本而转转于五道云下转，向始觉之本而转转云上转。(参见：下转)
（术语）本觉为化他而下向曰下转，始觉为自利而上进曰上转。又背本觉之本而转转于五道云下转，向始觉之本而转转云上转。(参见：下转)
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条