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1)  metalloproteinases/ tissue inhibition metalloproteinases
金属蛋白酶/抑制剂
2)  tissue inhibitor of metalloproteinase
组织金属蛋白酶抑制剂
1.
Tissue inhibitor of metalloproteinases(TIMPs)are the natural repressor of MMPs,the ratio between MMPs and TIMPs may be a significant target to reflect the activity and prognosis of RA.
组织金属蛋白酶抑制剂(TIMPs)是MMPs的天然抑制物,MMPs/TIMPs两者比例可作为反映疾病活动程度及预后的重要指标。
2.
Aim To investigate the mRNA levels of tissue inhibitor of metalloprot einase-1(TIMP-1),tissue inhibitor of metalloproteinase-2 (TIMP-2) in rat car diac fibroblasts by multiplex reverse transcription-polymerase chain reaction ( RT-PCR).
目的通过建立多重反转录聚合酶链反应(RT-PCR)方法,旨在测定大鼠心肌成纤维细胞组织金属蛋白酶抑制剂-1(TIMP-1)、组织金属蛋白酶抑制剂-2(TIMP-2)的mRNA水平。
3)  tissue inhibitor of metalloproteinase
基质金属蛋白酶抑制剂
1.
The matrix metalloproteinase(MMPs)/tissue inhibitor of metalloproteinase(TIMP)system plays a vital role in degrading and remodeling the extracellular matrix(ECM).
基质金属蛋白酶(MMPs)/基质金属蛋白酶抑制剂(TIMP)系统在降解和重塑细胞外基质(ECM)过程中发挥着重要的作用,同时这一酶系也参与了如:眼外伤、糖尿病性视网膜病变、增殖性玻璃体视网膜病变(PVR)、青光眼等常见眼科疾病的病理过程。
2.
Objective To study the function of MMP 2 (matrix metalloproteinase 2), MMP 9 (matrix metalloproteinase 9) and TIMP 1 (tissue inhibitor of metalloproteinase 1) in the pathogenesis of EAM (experimented autoimmune myositis) rats, and to evaluate the effect of methylprednisolone on the mRNA and protein expression of MMP 2, MMP 9 and TIMP 1.
目的 :探讨基质金属蛋白酶 (MMP 2 ,MMP 9)及基质金属蛋白酶抑制剂 (TIMP 1)在实验性自身免疫性肌炎 (EAM)发病中的作用 ,以及甲基强的松龙对MMP 2 ,MMP 9,TIMP 1基因mRNA和蛋白表达的影响。
4)  Tissue inhibitors of metalloproteinase
基质金属蛋白酶抑制剂
1.
Objective To identify metrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 , 2 in anterior segment tissues of normal human eyes and to determine the roles of metrix metalloproteinase ( MMP) and tissue inhibitors of metalloproteinase (TIMP) in trabecular outflow and uveoscleral outflow in normal eyes.
目的观察正常人眼前段组织中基质金属蛋白酶1(MMP-1)、基质金属蛋白酶抑制剂1(TIMP-1)和TIMP-2的表达,探讨正常生理状态下MMP及TIMP在小梁网房水流出及葡萄膜巩膜房水流出通道中的作用。
5)  TIMPs
基质金属蛋白酶抑制剂
6)  TIMP
金属蛋白酶组织抑制剂
1.
Objective:To determine the effect of acitretin on MMP-2 and TIMP-2 and to explore its treatment mechanism in the patients with psoriasis vulgaris.
目的:确定基质金属蛋白酶-2(MMP-2)及金属蛋白酶组织抑制剂-2(TIMP-2)在寻常型银屑病发病中的作用及阿维A对其的调节作用。
2.
Matrix metalloproteinases(MMP) and Tissue Inhibitor of metalloproteinases(TIMP) can regulate the degradation and synthesis of extracellar matrix(ECM), and participate in many physiogical and pathological processes in vivo.
基质金属蛋白酶 (MMP)和金属蛋白酶组织抑制剂 (TIMP)调节细胞外基质 (ECM)的分解与合成 ,参与体内多种生理病理过程。
补充资料:金属蛋白酶抑制剂
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性质:一类组成结构中含有一个或一个以上金属离子的蛋白酶,凡能抑制此类蛋白酶又不使酶蛋白变性的物质,都属于金属蛋白酶抑制剂。如,由田无链霉菌MD706-Y4产生的磷酰胺素(phosphoramidon),由马组链霉菌产生的塔罗肽(talopeptin)等都是金属蛋白酶抑制剂。

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