1) Cerebral cholinesterase
脑胆碱酯酶
3) cholinesterase
[英][,kɔli'nestəreis] [美][,kolə'nɛstə,res, -,rez]
胆碱酯酶
1.
Study on the detection of pesticide residues in vegetable with cholinesterase extracted from wheat;
小麦中胆碱酯酶的提取及其在蔬菜农药残留检测中的应用研究
2.
Study on screening of cholinesterase for the rapid detection of pesticide residues;
农药残留快速检测用酶——胆碱酯酶的筛选
3.
Neuroprotective effects of liquiritin and its inhibitory actions on cholinesterase activity;
甘草苷的神经保护及对胆碱酯酶的抑制作用
4) ChE
胆碱酯酶
1.
The evaluation of detecting ADA and CHE for acute hepatitis;
腺苷脱氨酶、胆碱酯酶检测在急性肝炎中的应用评价
2.
Objective To explore the relationship of serum Choline Esterase(ChE),Triglycerides (TG), Cholesterol(Ch),Alanine Aminotrasferase(ALT) ,γ-Glutamyl Transpeptidase (γ-GT) etc.
目的 :探讨血清甘油三酯 (TG)、总胆固醇 (CHOL )的浓度和丙氨酸氨基转氨酶 (AL T)、γ-谷氨酰转移酶(GGT)、胆碱酯酶 (Ch E)的活性与脂肪肝的关系。
3.
The models of the human brain AChE and human serum BuChE have been constructed on the basis of the putative three-dimensional structural similarity with Torpedo california AChE.
本文以同源的电鳐胆碱酯酶(T。
5) acetylcholinesterase
[英][,æsitilkəuli'nestəreis] [美][ə,sitl,kolə'nɛstə,res, -,rez]
胆碱酯酶
1.
Effects of subacute dimethoate administration on acetylcholinesterase and subtype of hepatic cytochrome P450 of rats;
乐果亚急性暴露对大鼠胆碱酯酶浓度及细胞色素P450亚型表达量的影响
2.
Serum Albumin,D-Dimer,and Acetylcholinesterase:Their Significance in Prognosis in Severe Sepsis;
重度脓毒症患者血清白蛋白、D-二聚体及胆碱酯酶水平的意义及预后的关系
3.
The inspection of the pesticide remains on the fruit and vegetable by acetylcholinesterase;
乙酰胆碱酯酶法检测果蔬农药残留的研究
6) AChE
[英][eɪk] [美][ek]
胆碱酯酶
1.
Effects of Soy Isofiavones on Brain AChE and Amino Acid Neurotransmitters and Memory of Mice;
大豆异黄酮对小鼠脑组织中胆碱酯酶和氨基酸类神经递质及记忆的影响
2.
Studies on the Phytosterones from Achyranthes Bidentata BI.: Extraction, Purification and the AChE Inhibition Effect;
牛膝甾酮类成分的提取分离和胆碱酯酶抑制作用研究
3.
Effects of Xanthoceras Sorbifolia Saponin on Function of Learning and Memory, and on Activity of AchE in Hippocampus and NGF in Submaxillary Gland;
文冠果皂甙对小鼠学习记忆功能及海马内胆碱酯酶和颌下腺内神经生长因子活性的影响
补充资料:胆碱酯酶抑制剂
胆碱酯酶抑制剂
Cholinesterase Inhibitors
danjianzhimei yiZhi」i胆碱醋酶抑制剂Cholinesterase Inhibitors李安良北京医科大学药学院概述··········································1··…883胆碱能神经传递的生物化学············……883乙酸胆碱醋酶的结构和作用机制······……884抑制胆碱醋酶的化合物············……”·…884氨基甲酸醋类······························……8844 .2.4 .3.5.6。参考文献安贝氯按····································……885磷酸衍生物·································……885胆碱幽酸抑制荆类杀虫剂的毒性······……886磷酸醋中毒的解毒荆·····················……886.‘·…,....····..……‘.·一。。.……。.0.…。。。。.·…8871.概述 可逆或不可逆地抑制胆碱酷酶(cholinesterase AChE)从而延缓乙酞胆碱(Acetyl比oline,Ach,l)分解的化合物称为胆碱酷酶抑制剂,又称抗乙酞胆碱酷酶药或间接胆碱能激动剂[l]。 O l十 CH犷一C一戒}一{HZ一一CHZ-一N(CH3)s(1) Ach是体内的胆碱能激动物质,存在于突触和神经效应器接头处,是胆碱能神经系统的神经递质。它可被AChE迅速催化水解而除去,水解产物为乙酸和胆碱。随着Ach的水解,其传递神经冲动的作用也就消失。了CHr戒卜-0一{Hr一毛HZ-weN(CH“),+H,o叹瓦矿了CHr州冬一OH+HO一CHZ一CH:一叫N(CH3), 胆碱酣酶抑制剂能抑制AChE,受体区ACh的浓度因AChE的失活而增加,对肌肉的刺激随之增强。胆碱醋酶抑制剂用于治疗重症肌无力和青光眼,由于作用持续时间较长,在治疗上优于胆碱能激动剂。有的化合物具有毒性和适宜的性质,成为杀虫剂或神经性毒气。2.胆碱能神经传递的生物化学 胆碱能神经内中枢神经冲动是通过动作电位传导的,Na+和K+是神经传递所涉及的重要离子。一旦接受神经冲动,Ach便从胆碱神经末梢的贮藏突触囊泡中释放出来。随后人Ch与突触后膜上的受体、运动终板或神经肌接头结合,从而改变接头后膜的通透性,使兴奋所必需的离子得以流动,由此实现冲动的传递。 Ach与受体的相互作用是可逆的。受体一ACh复合物解离后,所释出的Ach在AchE催化下迅速水解。由于水解的反应速度极快,所以从突触囊泡中所释出的ACh与受体结合后立即遭到破坏。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条