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1)  sulfonylurea drug
磺酰脲药物
1.
2 constitute β-cell ATP-sensitive potassium channel, which has an importantfunction on insulin excretion triggered by sulfonylurea drug and glucose.
胰岛β细胞膜表面的磺酰脲药物受体(SUR1)为ATP结合盒超蛋白家族成员,与内向整流钾离子通道Kir6。
2)  sulphonylureas
磺酰脲类药物
1.
Preliminary studies on relationship between sulphonylureas-induced hypoglycemia and CYP2C9 genotype in patients with type 2 diabetes;
磺酰脲类药物致2型糖尿病患者低血糖与CYP2C9基因型关系初步研究
3)  sulfonylureas
磺脲类药物
1.
Influence of sulfonylureas on cardiovascular system:progress in basic research and clinical research;
磺脲类药物对心血管系统影响的基础和临床研究进展
2.
Effect of novolin for patients with 2-DM by sulfonylureas failure;
诺和灵治疗磺脲类药物继发性失效疗效观察
3.
OBJECTIVE In order to know if sulfonylureas have adverse effects on the cardiolvascular system, we took healthy Newsland white rabbits and observed the effects of glibenclamide, glimepiride and glipizide on the protection from myocardial ischemic preconditioning(IPC).
目的 为了研究磺脲类药物对心肌缺血方面的作用,我们选取格列本脲、格列美脲、格列吡嗪等磺脲类药物,来了解这些药物对健康新西兰白兔心肌缺血预适应的影响。
4)  sulfonylurea [英][,sʌlfənil'juəriə]  [美][,sʌlfənɪljʊ'riə]
磺脲类药物
1.
Intensive therapy of continuous subcutaneous insulin infusion on diabetics with secondary sulfonylurea failure;
磺脲类药物继发性失效患者短期胰岛素泵强化治疗的临床观察
2.
AIM: To investigate the characteristics of expression and regional distribution of 2 subtypes of sulfonylurea receptors (SUR1 and SUR2) in the heart of immature and adult normal rat.
目的 :探索磺脲类药物受体 (SUR)亚型 SUR1和 SU R2在仔鼠及成年正常大鼠心肌中的定位、分布及表达特征。
3.
Objective: To compare the effect of different sulfonylureas(glibenclamide, glimepirde,gliclamide and glipizide) on the isolated rat heart myocardial protection afforded byischemic preconditioning, and observe their inhibition of ATP-sensitve potassiumcurrent of rat myocyte.
目的对比不同磺脲类药物:格列本脲、格列美脲、格列奇特和格列吡嗪对大鼠离体心脏心肌预缺血保护作用的影响,并观察它们对大鼠心肌细胞ATP依赖性钾通道电流的作用,为临床选择磺脲类药物提供参考。
5)  sulfaurea drugs
磺脲类药物
1.
The efficacy of glipizide XL in the treatment of type 2 diabetic patients unresponding to sulfaurea drugs;
格列吡嗪控释片对磺脲类药物疗效不佳的2型糖尿病患者的疗效观察
6)  sulphonylurea [,sʌlfənil'juəriə]
磺酰脲类降糖药
1.
Qualitative identification of illegal adding of sulphonylurea to antidiabetic food for health care;
保健食品中非法添加磺酰脲类降糖药的定性方法研究
补充资料:1[(对乙酰苯)磺酰]-3-环己脲
CAS:968-81-0
分子式:C15H20N2O4S
分子质量:324.420
中文名称:醋磺环已脲;醋磺环己脲;1[(对乙酰苯)磺酰]-3-环己脲

英文名称:1-((p-acetylphenyl)sulfonyl)-3-cyclohexyl-ure;1-((p-acetylphenyl)sulfonyl)-3-cyclohexylurea;1-(p-acetylbenzenesulfonyl)-3-cyclohexylure;4-acetyl-n-benzenesulfonamide;acetohexamid;4-acetyl-n-((cyclohexylamino)carbonyl)-benzenesulfonamid;4-acetyl-n-[(cyclohexylamino)carbonyl]-benzenesulfonamid;dimelin;dymelor;gamadiaber

性状描述:该品从90%乙醇中得到的结晶,熔点为188-190℃。溶于吡啶,微溶于醇和氯仿,不溶于水和醚。

生产方法:先由对氨基乙酰苯制取对乙酰苯磺酰胺,再继续与环已基异氰酸盐反应,得到醋磺环已脲。

用途:降血糖药。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条