1) siRNA plasmid
siRNA质粒
1.
We constructed a gremlin siRNA plasmid and delieved it to the STZ-induced diabetes mouse model, and observed the pathological changes, the cell prolifferationa and apoptosis, the changes of renal function and expression of BMP7 after administration of gremlin siRNA plasmid, to investigate the protective role of inhibition of Gremlin expression in DN.
本试验拟以发育相关因子Gremlin作为靶点,STZ诱导糖尿病小鼠模型,观察转染gremlin siRNA质粒对糖尿病小鼠肾脏病理学变化、肾脏细胞增殖凋亡情况、肾功能及BMP7表达等的影响,探讨抑制Gremlin表达后对肾脏的可能保护作用。
2) siRNA plasmid
siRNA表达质粒
1.
Anti-cancer mechanism of survivin siRNA plasmid mU6/survivin
存活素siRNA表达质粒mU6/survivin的抑癌机制研究
3) Plasmid-vector for siRNA
siRNA质粒表达载体
1.
Plasmid-vector for siRNA was constructed and transfected into ameloblastoma cells.
方法:培养成釉细胞瘤细胞,应用免疫组织化学方法检测成釉细胞瘤中MMP-2的表达;体外构建MMP-2靶向siRNA质粒表达载体,将siRNA质粒表达载体转染原代培养的成釉细胞瘤细胞,激光共聚焦显微镜检测siRNA质粒表达载体的转染效率,RT-PCR检测成釉细胞瘤细胞中MMP-2mRNA的改变,明胶酶谱法检测MMP-2的变化,应用SPSS11。
4) PTHrP chondrosarcoma
siRNA(PTHrp)质粒构建
5) siRNA library
siRNA质粒表达文库
6) small interfering RNA
siRNA
1.
Effect of small interfering RNA-mediated silencing of CD158b expression on the cytotoxicity of NK cells against the allogeneic dendritic cells;
SiRNA沉默NK细胞CD158b表达及对异体树突状细胞的杀伤作用
2.
Effect of small interfering RNA targeting multidrug resistance-related protein and bcl-2 on drug resistance and apoptosis of K562 and K562/ADM cells;
siRNA对K562和K562/ADM细胞耐药和凋亡的调节
3.
Construction of small interfering RNA targeting mouse vascular endothelial growth factor receptor-2:its serum stability and gene silencing efficiency in vitro
靶向VEGFR2基因的siRNA分子血清稳定性及其基因沉默效应
补充资料：PUC18质粒DNA
CAS: 9007-49-2
中文名称: PUC18质粒脱氧核糖核酸；PUC18质粒DNA
英文名称: Deoxyribonucleic-acid；Calf thymus DNA；Desoxyribose nucleic acid；DNA；Nucleic acids, deoxyribo；deoxyribonucleic ac.；Nucleic acids,deoxyribo
中文名称: PUC18质粒脱氧核糖核酸；PUC18质粒DNA
英文名称: Deoxyribonucleic-acid；Calf thymus DNA；Desoxyribose nucleic acid；DNA；Nucleic acids, deoxyribo；deoxyribonucleic ac.；Nucleic acids,deoxyribo
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