1) Hairpin siRNA
发卡样siRNA
3) small interfering RNA
siRNA
1.
Effect of small interfering RNA-mediated silencing of CD158b expression on the cytotoxicity of NK cells against the allogeneic dendritic cells;
SiRNA沉默NK细胞CD158b表达及对异体树突状细胞的杀伤作用
2.
Effect of small interfering RNA targeting multidrug resistance-related protein and bcl-2 on drug resistance and apoptosis of K562 and K562/ADM cells;
siRNA对K562和K562/ADM细胞耐药和凋亡的调节
3.
Construction of small interfering RNA targeting mouse vascular endothelial growth factor receptor-2:its serum stability and gene silencing efficiency in vitro
靶向VEGFR2基因的siRNA分子血清稳定性及其基因沉默效应
4) small interference RNA
siRNA
1.
Objective To evaluate the effectiveness of small interference RNA (siRNA) on inhibiting bcl-2 gene expression.
目的研究小干扰RNA(siRNA)对bcl-2基因表达的抑制作用。
2.
To study the regulation mechanism of HIF-1α in proliferation and differentiation of stem cells, two small interference RNA expression vectors of HIF-1α were constructed, and transfected into the fetal liver stromal cell lines (FLSCs) stably by lentiviral system.
为了研究低氧诱导因子(hypoxia inducible factor-1alpha,HIF-1α)在干细胞增殖分化过程中的作用机制,构建了2个HIF-1α慢病毒siRNA干涉载体,并转染人胎儿肝脏基质细胞(fetal liver stromal cell,FLSC)。
3.
Objective To study the effect of small interference RNA on E6, E7mRNA of human papillomavirus type-18(HPV18) in cervical cancer cells and its therapy action to cervical cancer.
目的 探讨siRNA(short interfering RNAs)对宫颈癌细胞人乳头状瘤病毒(HPV)18型E6、E7 mRNA表达的干扰作用。
5) RNAi
siRNA
1.
Conclusions:RNAi mediated by chemically modified siRNA efficiently knocked-down VEGFR-1 gene expression and inhibited cellular proliferation.
目的:体外水平探讨利用化学修饰的小干扰RNA(small interfering RNA,siRNA)敲减VEGFR-1基因治疗乳腺癌的可行性和特异性。
2.
Knockdown fusion gene SYT-SSX expression by RNAi induces apoptosis in synovial sarcoma cells line HS-SY-Ⅱ;
目的研究siRNA(smallinterferingRNA)对滑膜肉瘤细胞系HS-SY-II中融合基因SYT-SSX表达的抑制作用,为RNAi技术在肿瘤生物治疗中的应用提供实验基础。
6) short hairpin RNA
短发卡样RNA
1.
Objective To construct a plasmid expression vector coding for the short hairpin RNA(shRNA) targeting Twist mRNA.
目的:构建编码Twist mRNA的短发卡样RNA(shRNA)质粒表达载体,并筛选出基因沉默效果最明显的shRNA质粒表达载体。
补充资料：Sirna
sirna
small interfering rna (sirna)：是一种小rna分子（~21-25核苷酸），由dicer（rnaase ⅲ家族中对双链rna具有特异性的酶）加工而成。sirna是sirisc的主要成员，激发与之互补的目标mrna的沉默。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。