1)  Antifungal susceptibility testing
体外抗真菌药敏试验
2)  in vitro
体外
1.
Comparison of release characteristics between two mizolastine sustained release tablets in vitro;
2种咪唑斯汀缓释片的体外释放度比较
2.
Preparation of sinomenine gel and its skin penetration test in vitro;
青藤碱凝胶剂的制备及体外渗透性能研究
3.
Hysteroscopic findings and interventions in patients undergoing in vitro fertilization-embryo transfer;
宫腔镜技术在体外受精—胚胎移植失败患者中的应用
3)  in vivo
体外
1.
Study on the fibrinolytic speciality in vivo of extract from Dochi;
淡豆豉提取物的体外溶栓特性研究
2.
This paper studied the effects of lacto-bioactive peptides on the liver cells reproduction in vitro, the growth and non-special immune function of whole male in vivo through two feeding experiments.
本实验以全雄奥尼罗非鱼为试验对象,通过离体试验研究乳源活性肽对奥尼罗非鱼肝细胞体外增殖的作用,通过两期动物饲养试验研究乳源活性肽对罗非鱼生长和非特异性免疫功能的影响。
4)  external
体外
1.
The therapeutic effect of external high-frequency heat therapy on late cancer of digestive tracts;
体外高频热疗治疗晚期消化道肿瘤
2.
Based on the analysing deformation of external prestressed concrete beam, the total process from loading stage to fail stage was analyzed for external prestressed concrete beam by means of section force equation and deform accordance, and the ultimate stress of the tendon and the ultimate strength of the concrete beam were found out.
该文在分析体外预应力钢筋与混凝土主梁变形的基础上 ,通过截面内力平衡方程和变形协调关系 ,对体外预应力混凝土梁进行了从加载到破坏的全过程分析 ,得到了极限状态下体外筋的极限应力和混凝土梁的极限抗弯强度。
3.
In combating the serious corruptive cases with some Party officials, the Party should discipline the organization itself and its official members, and a performance appraisal system by external supervision can be introduced to reinforce and offset the on going Party member evaluating system so that the Party is governed with strict disciplines and supervision.
面对当前某些党员干部中存在严重的腐败现象 ,在坚持“党要管党”和“党管干部”的前提下 ,充分利用广大人民群众的监督作用 ,按照“三个”代表的要求 ,探索建立一种“体外”监督考评党员干部的制度 ,以加强和完善现行的党员民主评议制度 ,实现从严治党的目
5)  Vitro
体外
1.
Effects of Se on the Lipid Peroxidation of Liver and Brain in Vitro;
硒对肝脏脑体外脂质过氧化的影响
2.
Research of Hepatocyte-like Cells Formed from Human Umbilical Cord Blood Stem Cells in Vitro;
脐血干细胞体外分化为肝样细胞的实验研究
3.
To investigate the feasibility of induction mononuclear cells (MNCs) from human umbilical cord blood to hepatocyte-like cells with cytokines in vitro.
本实验探讨体外采用细胞因子诱导脐血单个核细胞(MNCs)定向分化为肝细胞的可能性。
6)  in vitro-in vivo extrapolation
体外-体外预测
参考词条
补充资料:抗真菌药和抗立克次氏体药


抗真菌药和抗立克次氏体药
Chemotherapeutics, Antimycotic and Antirickettsial

kans抗真菌药和抗立克次氏体药第9卷 O }}(1)CICH之一C一CHZCI一-~甲~~~~~叫~~一~~~(2)CHaC00H FB了IJ ︸胜、!尸以.纵扮!F(48) OH lCICH:一C一CHZCIN=,、 1,1 NH尸丫r,一一三之~、汗尸Na月,DMF F(49)(11) :HzN~3。:。您丫督自气丛立竺竺自护、-跳沪/、‘犷HCOH、屯/卜‘2 (51)(52) 。之丫⑧ 坐助OH(‘2,(53) HCI-~~,~~~~~~,..~ 一H20‘HCI(90)侧 月F C.\H一\l尸n下.C上z、丫F H C 一 N =‘ N 1.1七(47) 氟康哇口服吸收快而完全,半衰期长(22~32h)体内分布均匀,能很好的透过血脑屏障,并渗透到脑脊液内阳〕。口服100mg后,脑脊液平均浓度为血浆浓度的0.58一0.89倍。70%原药由肾脏排除。 大多数病人对氟康哇耐受良好哪〕。常见的副作用为头痛、恶心、疲劳、发热、浮肿、出疹、腹部不适及转氨酶升高。但发生率小于5环,极少数病人出现血小板减少,停药后即恢复。·2.8.烯丙胺类 1981年发现蔡替芬(haftifine)(s0)具有较高的广谱抗真菌活性。由于其优良的抗真菌活性,新颖的结构特点,很快引起了人们的重视,通过对其结构改造和抗菌活性的研究,发现了活性高、毒性低的衍生物特比禁芬(terbinafine)(‘oa)和丁禁芬(botenafine)(乐ob)。活性最大,最低抑菌浓度(Mlc)为。.01一0.2哆/ml,对申克氏抱子丝菌和曲霉属真菌次之,Mlc分别为0.8一1.5限/耐和0.8~12.5阳/而。禁替芬的体外抗皮肤真菌活性明显优于咪哇类抗真菌药,而与托蔡醋(发癣退)和灰黄霉素相似。 蔡替芬对真菌细胞超微结构有影响,还干扰真菌细胞的脂质代谢,故有杀菌作用。在作用机理上蔡替芬与氮哇类药物一样,都是抑制麦角幽醇的生物合成,但作用部位二者不同,禁替芬是角拨烯的环氧化酶的特异性抑制剂。通过抑制角鳖烯的环氧化,使角盆烯蓄积和麦角幽醉缺乏,使真菌细胞膜的组成和通透性发生改变,导致杀菌作用[5,〕。 蔡替芬是一个高效低毒的外用抗真菌药,其疗效与克霉哇、美康哇、益康哇等外用抗真菌药相似。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。