1) HIV-1 transactivator of transcription
HIV-1反式转录调节蛋白
2) YY1
转录调节蛋白
1.
The specific binding sites of YY1 protein are found in the flanking sequences ofnlany cellular aiid viral promoters.
为研究ＨＰＶ１６转录调节蛋白ＹＹ１结合位点改变对病毒致癌性的影响，以ＨＰＶ１６野毒株质粒ｐ１２０３为基础，经多次克隆，将来自宫颈癌组织并带有缺损突变的ＬＣＲ重组到地ＨＰＶ１６基因组中。
4) CRMP-1
坍塌反应调节蛋白-1
1.
Objective: To construct the CRMP-1-phrGFPⅡ-N mammalian expression vector and test the effects of up-regulation of the CRMP-1(Collapsin Response Mediator Protein-1) gene on axon outgrowth.
目的：构建CRMP-1-phrGFPⅡ-N真核表达载体，探讨坍塌反应调节蛋白-1(Collapsin Response Mediator Protein-1，CRMP-1)过表达情况下对细胞突起生长的影响。
5) HIV 1 protease
HIV-1蛋白酶
1.
The algorithm is applied to the docking of several simple model molecules and the docking between the benzamidine and HIV 1 protease.
首先将该算法应用于假想分子模型间的刚性对接 ,然后将算法应用于 HIV-1蛋白酶与苯甲醚配体的刚性对接 。
6) HIV-1 protease
HIV-1蛋白酶
1.
Because HIV-1 protease is responsible for the cleavage of the gag and pol nonfunctional polypeptides into mature and functional HIV viral particles that can infect a host cell in the life cycle of the HIV virus, it is significant to investigate the interaction mechanism of HIV protease with inhibitors for the design of inhibitors targeting HIV protease.
多年以来,HIV-1蛋白酶已经成为研发抗HIV新药的一个重要靶点。
2.
HIV-1 protease (PR) is one of the primary targets for drug development against HIV-1 infection due to its key role in viral maturation.
HIV-1蛋白酶(Protease, PR)在HIV-1病毒多肽形成过程中起着重要作用,它对HIV-1的复制是必要的,因此HIV-1 PR是艾滋病即获得性免疫缺陷综合症(Acquired Immunodeficiency Syndrome, AIDS)治疗的主要药物靶点之一。
3.
The protonation state of Asp25/Asp25\' in Protease-Indinavir (PR-IDV) complex is important for HIV-1 protease to study the binding mechanism and the drug resistance induced by the mutation in theory.
I型人体免疫缺陷病毒(HIV-1)蛋白酶中Asp25/Asp25\'的质子化对于理论研究HIV-1蛋白酶和抑制剂的作用机制以及氨基酸变异对抗药性的影响有重要意义。
补充资料：反式,反式-1,3-丁二烯-1,4-二羧酸
分子式：C6H6O4
分子量：142.11
CAS号：3588-17-8
性质：熔点290°C (dec.)。沸点320°C。水溶性insoluble。
分子量：142.11
CAS号：3588-17-8
性质：熔点290°C (dec.)。沸点320°C。水溶性insoluble。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条