1)  bestatin
bestatin
1.
This study was purposed to investigate whether aminopeptidase inhibitor, bestatin, can potentiate all-trans retinoic acid (ATRA)-inducing differentiation in NB4 cells, and to explore its mechanism.
为了研究氨肽酶抑制剂乌苯美司(bestatin)对全反式维甲酸(ATRA)诱导人APL细胞株NB4细胞分化作用的影响及其可能机制,NB4细胞经bestatin和ATRA单用或联合应用处理一定时间后,用光学显微镜观察细胞形态,流式细胞仪检测CD11b表达,四氮唑蓝(NBT)还原实验检测分化细胞功能,RT-PCR法检测c-myc和c-EBPεmRNA表达,Westernblot检测c-Myc蛋白表达。
2.
We have employed bestatin as a small molecular chemical tool to dissect jasmonic acid signaling in Arabidopsis and identified a collection of bestatin response (ber) mutants.
bestatin是一种氨肽酶抑制剂,能够激活茉莉酸信号转导途径而诱导抗性相关基因的表达,从而为用化学遗传学手段解析茉莉酸途径提供了一个有效的工具。
3.
Bestatin, a potent inhibitor of some aminopeptidases, was shown previously to be a powerful inducer of wound response genes in tomato.
我们以番茄和拟南芥中茉莉酸合成和信号传导突变体为材料,利用遗传学和生理生化手段证明bestatin可以特异性的激活植物体内的茉莉酸信号转导途径。
2)  bestatin
脑啡肽的氨基肽酶抑制剂
3)  Bestatin
乌苯美司
1.
Bestatin potentiates ATRA induced differentiation in NB4 cells possibly through down-regulation of c-myc expression;
乌苯美司下调c-myc表达与其增强全反式维甲酸诱导NB4细胞分化作用关系的实验研究
2.
Synthesis of the key intermediate of bestatin;
乌苯美司关键中间体的合成
3.
Amino-2-hydroxy-4-phenylbutanoic acid(compound 3), the key intermediate for the synthesis of Bestatin, was prepared via substitution, condensation and reduction in an overall yield of about 47.
乌苯美司(Bestatin)能有效地抑制氨肽酶B和亮氨酸氨肽酶的活性[1],对急性白血病、恶性黑色素 瘤等有显著疗效。
4)  Bestatin
百士欣胶囊
5)  Bestatin
威迪凯
6)  Obestatin
Obestatin
1.
Obestatin and ghrelin are two important brain-gut peptides that can combine with their receptors and exert important biological functions.
Obestatin位于胃生长素前体原的76-98片段,可以结合孤儿G蛋白GPR39受体,抑制食物摄取、空肠的蠕动和体质量的增加。
2.
Objective:To investigate the inhibitory effects of obestatin on proliferation and differentiation of 3T3-L1 preadipocytes.
目的:观察obestatin对3T3-L1前脂肪细胞增殖分化的影响。
3.
Objective To investigate the effect of obestatin on proliferation and differentiation of 3T3-L1 preadipocyte and explore the related mechanism.
目的观察obestatin对3T3-L1前脂肪细胞增殖分化的影响并探讨其作用机制。
参考词条
补充资料:Bestatin
分子式:C16H24N2O4
分子量:暂无
CAS号:58970-76-6

性质:暂无

制备方法:暂无

用途:急、慢性细胞性白血病等病的辅助治疗

说明:补充资料仅用于学习参考,请勿用于其它任何用途。