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1)  rmhTNF(TNF-α mutant)
纳科思(TNF-α变构体)
2)  human TNF α mutein 471
人突变体471 TNF-α
3)  transmembrane TNF-αmutein
跨膜型TNF-α突变体
4)  anti-TNF-α antibody
抗TNF-α抗体
5)  tumor necrosis factor
TNF-α
1.
Different levels of taurine and β-alanine were added to deterrmine the blood pressure,activity of plasma renin activity,content of adrenomedullin,tumor necrosis factor and content of insulin-like growth factor effecting on hypertension in rat blood to probing into whether taurine has effect on hypertension.
通过检测补充不同水平牛磺酸和β-丙氨酸(牛磺酸转运抑制剂)大鼠的血压和血液中血浆肾素活性(PRA)、肾上腺髓质素(ADM)、血清肿瘤坏死因子(TNF-α)、胰岛素样生长因子-Ⅰ(IGF-Ⅰ)的含量,探讨牛磺酸对高血压发生的预防作用。
2.
Objective To investigate the effect of meglumine cyclic adenosine monophosphate(M-cAMP) on the serum levels of interleukin(IL)-6,IL-10 and tumor necrosis factor(TNF)-α in infant patients with congenital heart disease undergoing cardiopulmonary bypass(CPB).
目的观察婴幼儿先心病患者在心内直视手术麻醉过程中应用环磷酸腺苷葡胺后血清中TNF-α、IL-6、IL-10的动态变化。
3.
Objective to:investigate the pathogenetic roles of tumor necrosis factor-α(TNF-α)and sex hormone and the correlation between these factors in collagen-induced arthritis during the early stage.
同步观察大鼠胶原诱导性关节炎早期血浆肿瘤坏死因子-α(TNF-α)与性激素水平的变化,探讨TNF-α和性激素在类风湿关节炎(RA)发病中的作用及其相关性。
6)  Tumor necrosis factor-α
TNF-α
1.
Relationship of serum free fatty acids and tumor necrosis factor-α in patient with type 2 diabetic retinopathy;
血清游离脂肪酸、TNF-α与2型糖尿病视网膜病变的关系
2.
Study of the relationship of the radionuclide bone scan with the levels of serum cytokine interleukin1β,interleukin-6,tumor necrosis factor-α and transforming growth factor-α in patients with osseous metastasis tumor;
骨转移瘤核素骨显像与血清IL-1β、IL-6、TNF-α、TGF-α水平关系的研究
3.
Observation of trends of nuclear factor-κB, tumor necrosis factor-α and pathologic injury in rats with acute pancreatitis;
急性胰腺炎大鼠核因子-κB、TNF-α及胰腺病理损伤的动态变化
补充资料:α,α,α,α',α',α'-六氯对二甲苯
分子式:C8H4Cl6
分子量:312.84
CAS号:68-36-0

性质:白色针状或粉末状结晶。熔点108-110℃。溶于二甲苯、石油醚、乙醇、植物油,不溶于水。无味,有特殊臭味,遇光、碱会缓慢分解而呈酸性。

制备方法:以混二甲苯为原料,先用98%硫酸磺化,使间二甲苯生成间二甲苯磺酸盐。从磺化反应物中分离出含邻、对二甲苯的油层,水洗、干燥,减压蒸馏出邻、对二甲苯。间二甲苯磺酸盐经水解可得副产品间二甲苯。由邻、对二甲苯经氯化即得1,4-双(三氯甲基)苯:在反应锅中投入邻、对二甲苯,再加入过氧化苯甲酰和三乙醇胺。加热到70℃后,在光照射下导入氯气,于70-80℃反应6h,再升温至100-120℃继续反应,至反应液相对密度达到1.560-1.580(65℃),即为反应终点,停止通氯,减压脱除余氯。降温至5℃,过滤,洗涤得粗品,重结晶,活性炭脱色得成品。

用途:抗血吸虫病药物。对肝吸虫病、阿米巴原虫病、疟疾以及肠道线虫有一定疗效。但对神经系统的不良反应较多见,且延迟反应持续较久。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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