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1)  hepatocytes-targeting
肝实质细胞靶向
1.
Transfection and anti-HBV effect mediated by the hepatocytes-targeting cationic liposomes co-modified with β-sitosterol-β-D-glucoside and Brij 35;
谷甾醇葡萄糖苷和卞泽双重修饰肝实质细胞靶向阳性脂质体介导的基因转染和抗乙肝病毒作用
2)  hepatocyte targeting
肝细胞靶向性
1.
Objective By taking advantage of Asialoglycoprotein receptor ( ASGPR) existing on the surface of hepatocytes, an experiment was conducted on the vp3 gene hepatocyte targeting therapy for hepatoma mediated by ASGPR.
目的利用肝细胞表面存在特异的脱唾液酸糖蛋白受体(asialoglycoprotein receptor,ASGPR),探索ASGPR介导的vp3基因肝细胞靶向性治疗肝癌的方法。
3)  Hepatocarcinoma cells targeting
肝癌细胞靶向
4)  Hepatocytes
肝实质细胞
1.
Aim: To investigate the protective effects of rosiglitazone on rat hepatocytes damaged by cyclosporine A.
目的:观察免疫抑制剂环孢素A(CsA)对大鼠肝实质细胞(BRL)增生及转化生长因子β1(TGF-β1)分泌的影响以及罗格列酮的干预作用。
2.
Hepatic stem cells are a group of cells in liver that have the self-renewal capability and multi-differentiation potential,including oval cells,small hepatocytes and small hepatocyte-like progenitor cells.
肝干细胞能分化为肝实质细胞和胆管上皮细胞,在一定条件下,还能分化为胰腺细胞、肠上皮细胞、肌细胞或转化为肝肿瘤细胞。
5)  hepatocyte [英]['hepətəsait]  [美]['hɛpətə,saɪt, hɪ'pætə-]
肝实质细胞
1.
The protective effect of the extracts of Rhizoma Picrorhizae on primary cultured hepatocytes injured by CCl 4 and D-GaIN was studied.
为研究胡黄连提取物对四氯化碳 (CCl4 )或半乳糖胺 (D GaIN)损伤原代培养大鼠肝实质细胞的保护作用。
2.
A new method was introduced to isolate and identify rat hepatocytes in this paper.
介绍一种分离、鉴定肝实质细胞的新方法。
6)  Cellular targeting
细胞靶向
1.
Cellular targeting and subcellular distribution of HER-2 targeting boron liposomes;
HER-2靶向硼脂质体的细胞靶向与细胞内分布研究
补充资料:肝靶向药物
分子式:
CAS号:

性质:利用肝细胞表面独特的无唾液酸糖蛋白受体定向地选择性地到达肝脏病变部位的药物。可避免或减少药物对非靶部位的作用,以消除或减轻毒副反应;可在病灶区浓集药物,以增强药物的药理作用。例如正定霉素(DNR)可以与接上了半乳糖末端残基的入血清白蛋白结合成肝靶向药物(DNR-Gal-HSA),用于肝癌的治疗,使70%的药物浓集在肝脏,降低药物的毒副反应。

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