1) Liver targeting
肝靶向
1.
Study on the liver targeting of oleanolic acid loaded polybutylcyanoacrylate nanocapsules in mice;
齐墩果酸聚氰基丙烯酸正丁酯纳米囊在小鼠体内的肝靶向研究
2.
Liver targeting of galactosylated liposome-polycation-DNA complexes;
半乳糖化脂质体-聚阳离子-DNA复合物的肝靶向性研究
3.
Study on the distribution and liver targeting of norcantharidin nanoparticles in mice;
去甲斑蝥素壳聚糖纳米粒在小鼠体内分布及肝靶向作用
2) hepatic targeting
肝靶向
1.
Synthesis and characterization of galactosyl-HSA (a hepatic targeting drug carrier);
肝靶向药物载体半乳糖基蛋白的合成及其特性研究
2.
To design and synthesize the hepatic targeting anticancer prodrug with norcantharidin (NCTD-Gal) conjugating structure, galactosylated NCTD derivatives were synthesized from NCTD analogues modified by a series of amino acids via acylation, hydrolysis, glycosylation and deacetylation.
设计并合成了肝靶向抗癌前药去甲斑蝥素-半乳糖(NCTD-Gal)偶联物。
3.
Objective:To design and synthesize NCTD-Gal derivatives as hepatic targeting prodrug.
目的:设计并合成去甲斑蟊素-半乳糖(NCTD-Gal)偶联物的肝靶向前药。
3) liver target
肝靶向
1.
Research of bile acids as carriers of liver targeted antitumor drugs;
以胆酸为载体的肝靶向抗肿瘤药物的研究
2.
OBJECTIVE To study the pharmacokinetics and tissue distribution of oxymatrine-SLN in animal and investigate the liver targeting effect of oxymatrine-SLN.
目的研究苦参素固体脂质体纳米粒(SLN)的动物体内行为,探讨苦参素SLN作为肝靶向给药系统的可行性。
3.
Objective:To study the tissue distribution of diammonium glycyrrhizinate(DG) and its phospholipid complex(DGPC) injection in mice and investigate the liver targeting effect of DGPC.
目的:研究比较甘草酸二铵及其磷脂复合物注射液在小鼠体内的组织分布,探讨甘草酸二铵磷脂复合物作为肝靶向药物的可行性。
4) Liver-targeting
肝靶向
1.
Preparation and Characterization of Liver-targeting Mitomycin C-polybutylcyanoacrylate Nanoparticles;
肝靶向丝裂霉素C-聚氰基丙烯酸正丁酯毫微粒的制备与表征
5) Hepatocyte-targeting
肝靶向
1.
Content determination of cucurbitacin B in galactosylated hepatocyte-targeting liposomes by RP-HPLC;
RP-HPLC法测定半乳糖化肝靶向葫芦素B脂质体中药物含量
2.
Objective To synthesize N-galactosylated chitosan as hepatocyte-targeting carrier and prepare loading norcantharidin nanoparticles.
目的合成N-乳糖酰壳聚糖作为肝靶向载体,制备去甲斑蝥素纳米粒。
6) Liver targeting
肝靶向性
1.
Effect of diameter of adriamycin polybutylcyanoacrylate nanoparticles on liver targeting;
阿霉素聚氰基丙烯酸正丁酯纳米粒粒径对肝靶向性的影响
2.
Preparation and liver targeting of floxuridinyl dibutyrate solid lipid nanoparticles;
氟尿苷二丁酸酯固体脂质纳米粒的制备和肝靶向性研究
补充资料：肝靶向药物
分子式：
CAS号：
性质：利用肝细胞表面独特的无唾液酸糖蛋白受体定向地选择性地到达肝脏病变部位的药物。可避免或减少药物对非靶部位的作用，以消除或减轻毒副反应；可在病灶区浓集药物，以增强药物的药理作用。例如正定霉素(DNR)可以与接上了半乳糖末端残基的入血清白蛋白结合成肝靶向药物(DNR-Gal-HSA)，用于肝癌的治疗，使70％的药物浓集在肝脏，降低药物的毒副反应。
CAS号：
性质：利用肝细胞表面独特的无唾液酸糖蛋白受体定向地选择性地到达肝脏病变部位的药物。可避免或减少药物对非靶部位的作用，以消除或减轻毒副反应；可在病灶区浓集药物，以增强药物的药理作用。例如正定霉素(DNR)可以与接上了半乳糖末端残基的入血清白蛋白结合成肝靶向药物(DNR-Gal-HSA)，用于肝癌的治疗，使70％的药物浓集在肝脏，降低药物的毒副反应。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条