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1)  Dual-color fluorescence hybridization
双色荧光杂交
2)  two-color fluorescence in situ hybridization
双色荧光原位杂交
1.
Detection of numerical aberrations of chromosomes 7 and 8 in sperms of workers exposed to benzene series by two-color fluorescence in situ hybridization;
双色荧光原位杂交检测苯系物接触者精子7、8号染色体数目畸变
3)  22q11.2 deletion
双色细菌人工染色体-荧光原位杂交
4)  DD-FISH
间期双色双融合荧光原位杂交
5)  triple-color fluorescence in situ hybridization
三色荧光原位杂交
1.
Objective: To analyze the numerical aberration of chromosome X, Y and 18 in the spermatozoa of asthenospermia patients by triple-color fluorescence in situ hybridization.
目的:利用三色荧光原位杂交方法分析弱精子症患者精子X,Y,18号染色体数目畸变。
6)  Multicolor fluorescence in situ hybridization
多色荧光原位杂交
1.
The clinical application of multicolor fluorescence in situ hybridization;
多色荧光原位杂交技术的临床应用
2.
Methods A complex chromosomal rearrangement (CCR) invol ved in chromosomes 5, 16 and 20 in a 29-year-old male carrier was determined b y chro mosomal microdissection and multicolor fluorescence in situ hybridization(M -FIS H), and family degree investigation was further performed.
方法对1例涉及5号、16号和20号染色体复杂重排核型的男性携带者,应用多色荧光原位杂交和显微切割技术进一步分析确定其核型,并进行家系调查。
3.
We elaborated a 47, XY, inv(9)(p11q13), +mar and a 46,XY,t(5;?) by combining a range of cytogenetic techniques, including multicolor fluorescence in situ hybridization (M-FISH), G-banding and NOR.
用多色荧光原位杂交技术结合G显带技术和NOR技术,对1例47,XY,inv(9)(p11q13),+mar和1例46,XY,t(5;?)核型进行诊断。
补充资料:荧光原位杂交


荧光原位杂交


是以荧光素标记取代核素标记而形成的一种新的原位杂交方法。利用已知碱基序列的非核素标记的核酸探针,依据碱基配对原理,通过免疫细胞化学检测体系,在组织切片、细胞间期核或染色体等标本上,进行DNA定性、定位及定量分析。本法快速、安全、灵敏度高,特异性强。
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