1) chronic constriction injury
慢性挤压伤
1.
Objective To evaluate the effect of intrathecal administration of ω-conopeptide SO3 on inducible nitric oxide synthase(iNOS)expression of spinal cord and the ligated sciatic nerve in a rat model with chronic constriction injury(CCI).
目的通过检测鞘内注射ω-芋螺毒素SO3对坐骨神经慢性挤压伤(CCI)模型大鼠脊髓及坐骨神经诱生型一氧化氮合酶(iNOS)蛋白表达的影响,探讨慢性神经痛发展过程中Ca2+对iNOS的作用。
2.
Objective To investigate the effect of intrathecal administration of ω-conopeptide SO3,a new N-type calcium channel blocker,on the expression of CGRP and substance P in the spinal cord of a rat model of chronic constriction injury(CCI).
目的通过研究鞘内注射新型N型钙通道阻滞剂ω-芋螺毒素SO3对坐骨神经慢性挤压伤(CCI)模型大鼠脊髓降钙素基因相关肽(CGRP)、P物质(SP)含量的影响,探讨N型钙通道在伤害性信息传递中的作用。
2) chronic constriction injury
坐骨神经慢性挤压伤
1.
AIM: To investigate the effect of intrathecal administration of ω-conopeptide SO_3, a neotype N-type calcium channel blocker, on the expression of Fos and Jun protein in the spinal cord of a rat model of chronic constriction injury (CCI).
通过研究鞘内注射ω-芋螺毒素SO3对坐骨神经慢性挤压伤(CCI模型)大鼠脊髓Fos、Jun蛋白表达的影响,探讨N型钙通道在伤害性信息传递中的作用。
2.
Objective: To investigate the changes of serum interleukin-6(IL-6) induced by chronic constriction injury(CCI) of sciatic nerve,and to determine the role of IL-6 in the development of neuropathic pain.
目的:通过大鼠坐骨神经慢性挤压伤(CC I)神经性疼痛模型的热敏变化及血清中IL-6含量的变化,探讨血清IL-6在神经性疼痛形成中的作用及可能机制。
3) Chronic constriction injury
慢性压迫性损伤
1.
Objective: To investigate the changes of c-jun in dorsal root ganglion(DRG) neurons in chronic constriction injury(CCI) model of chronic neuropathic pain.
目的观察大鼠背根神经节(DRG)中即刻早期基因(IEG s)c-jun在慢性压迫性损伤(CC I)疼痛模型中的变化,探讨慢性神经痛的发生机制。
4) chronic constriction injury
慢性压榨性损伤
1.
The thermal hyperalgesia in rats with chronic constriction injury of sciatic nerve is related to the lymphocyte-involved mechanism;
坐骨神经慢性压榨性损伤大鼠的热痛敏与淋巴细胞参与的免疫机制有关
5) chronic constriction injury
慢性压迫损伤
1.
Objective To observe the ultrastructure changes of sensory neurons in the spinal dorsal horn after chronic constriction injury(CCI) of the sciatic nerve in rats.
目的观察大鼠坐骨神经慢性压迫损伤后脊髓背角浅层神经元超微形态变化。
2.
Chronic constriction injury (CCI) model was established in rats of operated groups.
目的:观察大鼠坐骨神经慢性压迫损伤后脊髓背角感觉神经元是否发生非凋亡性细胞程序性死亡(paraptosis)。
6) reverse squeeze
可逆性挤压伤
补充资料：挤压伤
挤压伤
crush injury
机体受巨大压力或冲击力作用使大范围的皮下组织和肌肉受挤压或捻挫而无皮肤破裂的损伤。受压部位解除压迫后可出现广泛出血、血栓形成、组织坏死及严重的炎症反应。伤后严重的肿胀及组织内压增高会阻碍肢体血循环，减少血容量；大量失活细胞崩解物的吸收，可引发急性肾功能衰竭。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条