2) antiepileptic
['ænti,epi'leptik]
抗癫痫药
1.
Synthesis of the antiepileptic tiagabine hydrochloride;
新型抗癫痫药盐酸噻加宾的合成
2.
Starting from tetrafuran, 2_(4_Aminosulfonylphenyl)_4H_1,2_thiazine_1_dioxide, an antiepileptic drug with special structure, was obtained via esterification, sulphonation, chloridization, condensation and cyclization.
以四氢呋喃为原料 ,经酯化、磺化、酰氯化、缩合、环化等步骤 ,合成了化学名为 4_(四氢_2H_1,2_噻嗪基_2 )苯磺酰胺_S_S_二氧化物的抗癫痫药舒噻嗪 (sulthiame) ,通过IR、1HNMR和元素分析对其结构进行了表
3.
Lamotigine is a new and specific antiepileptic.
拉莫三嗪是一种新型的特效抗癫痫药，我国对该药的应用完全依赖于从英国进口。
3) antiepileptic drug
抗癫痫药
1.
Gabapentin hydrochloride, an antiepileptic drug, was synthesized by Knoevenagel reaction from cyclohexanone and acetonitrile, Michael addition reaction, Pd-C catalytic hydrogenation and hydrolysis to give 2-hydroxy-2-azaspiro[4.
5]癸烷-3-酮,再经RaneyNi催化氢化还原和水解、成盐制得抗癫痫药盐酸加巴喷丁,总收率14%。
2.
Objective:The results of serum concentration monitoring of 4 antiepileptic drugs with 357 measurements in 164 epilepsy children were evaluated in order to guide clinical rational administration of these antiepileptic drugs.
目的:回顾性分析4种常用抗癫痫药在儿童癫痫治疗中的血药浓度监测情况,以利指导合理用药。
4) antiepileptics
抗癫痫药
1.
Advance in research of fetal malformations induced by antiepileptics;
抗癫痫药致胎儿畸形的研究进展
2.
Effect of hemolysis in antiepileptics plasma sample determined by FPIA;
溶血现象对抗癫痫药血药浓度测定的影响
5) Antiepileptic drugs
抗癫痫药
1.
Advances in studies on population pharmacokinetics of antiepileptic drugs and CYP450 gene polymorphisms;
抗癫痫药的群体药代动力学与CYP450基因多态性的研究进展
2.
Antioxidants protects against peripheral nerve damages induced by antiepileptic drugs in rats;
抗氧化剂防治抗癫痫药所致周围神经损伤的实验性研究
3.
Objective: To study the bone metabolism in patients with epilepsy after antiepileptic drugs (AEDs) treatment.
目的 :探讨抗癫痫药对癫痫患者骨代谢影响。
6) anti-epilepsy drugs
抗癫痫药
1.
Simultaneous determination of concentration of 5 anti-epilepsy drugs in plasma by solid phase extration RP-HPLC method;
SPE-HPLC法同时测定5种抗癫痫药的血药浓度
2.
Retrospective analysis on anti-epilepsy drugs serum concentration in 660 cases;
660例抗癫痫药血药浓度监测分析
补充资料：抗癫痫药血清浓度监测
抗癫痫药血清浓度监测
monitoring of serum concentration of antiepileptic drugs
通过血清中抗癫痫药物浓度的测定来指导癫痫治疗的一种方法。常用的有分光光度计法、薄层层析法、气相层析-色谱法、气-液层析法、高压液相层析法、放射免疫分析法、酶多相免疫测定法等。以气-液层析法应用最广，酶多相免疫测定法最精确。目前可对苯妥英钠、苯巴比妥、丙戊酸钠、卡马西平、扑痫酮和安定类药物等进行测定。监测指征：①抗癫痫药超量仍不能控制发作；②剂量和血浓度间不协调；③出现中毒症状；④发作尚未控制而又无法判断是剂量不足或过量；⑤服用安全范围小的药物；⑥多种药物联合应用；⑦科研或对比疗效。药物血清浓度监测需达稳态后进行，主要用于指导合理用药，监测和提高疗效，减少用药量及毒副作用。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条