1) conditionally replicating adenovirus
肿瘤增殖型腺病毒
1.
Objective To construct the conditionally replicating adenovirus vector Ad-delE1b55kD-shRNA/Survivin-EGFP that can transfects into HT-29 effectually and selectively and contains shRNA targeting to human Survivin gene.
目的构建特异性强,转染率高,针对人Survivin进行RNA干扰的肿瘤增殖型腺病毒载体(Ad-delE1b55kD-shRNA/Survivin-EGFP)。
2.
Objective To Construct the conditionally replicating adenovirus vector Ad-delE1b55KD-shRNA/Survivin-EGFP which can transfect to HT-29 effectually and selectively and containing shRNA to human Survivin gene.
目的:构建特异性强,转染率高,携带针对人Survivin的shRNA的肿瘤增殖型腺病毒载体,研究其介导的以人Survivin为靶标的RNA干扰对结肠癌细胞株HT-29中Survivin mRNA和蛋白的表达、对结肠癌细胞HT-29增殖和凋亡的影响、时效性及其意义,探讨肿瘤增殖型腺病毒介导RNA干扰对结肠癌的治疗作用。
2) replication-competent adenovirus
肿瘤特异增殖型腺病毒
1.
Construction of replication-competent adenovirus shuttle plasmids pAd-delE1b55kD;
肿瘤特异增殖型腺病毒穿梭质粒pAd-delE1b55kD的构建
3) replicative adenovirus
肿瘤增殖病毒
4) conditionally replicating adenovirus
增殖型腺病毒
1.
Infection of tumor cells with conditionally replicating adenovirus results in tumor-specific replication,subsequent oncolysis and release of the virus progeny.
增殖型腺病毒能在肿瘤细胞中复制并裂解肿瘤细胞,释放出的子代病毒再感染邻近肿瘤细胞直至完全杀灭肿瘤,却不影响正常细胞的功能。
5) Replication competent adenovirus
增殖型腺病毒
1.
Methods Replication competent adenovirus and replication competent adenovirus mediated interleukin 12 gene was constructed and expanded separately.
目的研究携带白介素12(mIL-12)基因的增殖型腺病毒CNHK200-mIL-12对胃癌细胞株化疗敏感性的影响。
2.
Objective:To construct a replication competent adenovirus vector carrying human endostatin gene,looking for an effective method for the therapy of colon cancer.
目的 :构建携带内皮抑素基因的增殖型腺病毒载体 ,寻找结肠癌的有效治疗方法。
6) replication-defective adenovirus
非增殖型腺病毒
1.
Part One Reconstruction and identification of the replication-defective /replication-competent virus expressing lipocalin 2 gene Objective To reconstruct replication-selective oncolytic adenovirus and replication-defective adenovirus,which can both express lipocalin 2 gene.
一、携带Lipocalin 2的靶向溶瘤腺病毒和非增殖型腺病毒的构建和鉴定 目的:构建携带人Lipocalin 2基因且删除E1B55基因的溶瘤腺病毒和携带Lipocalin 2的非增殖型腺病毒。
补充资料：咽后增殖腺肥大
咽后增殖腺肥大
adenoidal hypertrophy
指儿童期咽扁桃体反复感染发炎而肥大。肥大的增殖体可大如核桃，妨碍鼻腔空气的流通，阻止鼻咽部分泌物的排出，堵塞咽鼓管口，影响中耳的通气与引流。患儿呈“增殖体面容”，张口呼吸、鼻根下陷、鼻翼萎缩，嘴唇甚厚、鼻唇沟变浅、上唇短而上翻、上门齿暴露突出、面容呆板、无表情，因呼吸困难可发生漏斗胸或鸡胸，夜晚睡眠不安。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条