1) Insulin-like growth factor 1
IGF-1
1.
Treatment and control skin tissue of sheep were sampled respectively for 0,3,6,9,12 and 50 days and the skin expression of growth hormone receptor(GHR),insulin-like growth factor 1(IGF-1),insulin-like growth factor receptor 1(IGF-1R),KAP3.
5mL(10ng/mL)的IGF-1,右侧肩胛部皮肤为未注射IGF-1的对照组,然后分别于第0、3、6、9、12、50d采集各皮肤样品,用反转录多聚酶链式反应(RT-PCR)方法,定量分析绵羊皮肤中生长激素受体(GHR)、胰岛素样生长因子1(IGF-1)和胰岛素样生长因子1型受体(IGF-1R)、角蛋白关联蛋白KAP3。
2.
Objective To investigate the roles of phosphatase and tensin homolog deleted on chromosome 10(PTEN),insulin-like growth factor 1(IGF-1),and insulin-like growth factor receptor 1 (IGF-1R) in the tumorigenesis,development,invasion and metastasis,and prognostic value of gastric cancer.
目的探讨PTEN、IGF-1、IGF-1R蛋白表达在胃癌发生、发展、侵袭转移及预后评价中的作用。
2) IGF-1 receptor
IGF-1受体
1.
Objective To observe the changes of IGF-1 receptors in uterine leiomyoma and its correlation with estrogen receptor,progesterone receptor,PCNA and Bcl-2.
目的观察人子宫肌瘤及周围正常子宫平滑肌组织中IGF-1受体、雌、孕激素受体、PCNA及Bcl-2含量的区别,并分析其相互关系。
2.
In 3T3-L1 cells, IGF-1 receptor is located in lipid rafts and caveolae of the plasma membrane and can directly interact with caveolin-1, the major protein component in caveolae.
我们的研究发现在3T3-L1前脂肪细胞分化诱导过程中，细胞膜上的脂质筏和质膜微囊结构对IGF-1受体的跨膜信号转导具有重要的作用，IGF-1受体的信号转导需要细胞膜上完整的脂质筏和质膜微囊结构。
3.
Results Stimulation of D_1-like receptor inhibited the IGF-1 receptor expression,which was blocked by D_1-like receptor antagonist.
方法本试验以A10细胞为研究对象,免疫印迹观察刺激D_1类受体对IGF-1受体表达的影响,并初步探讨D_1类受体对IGF-1受体影响的机制。
3) IGF-I gene
IGF-1基因
1.
The genetic variation of the 5 region of the IGF-I gene in rose cockscomb chickens was detected by PCR-RFLP.
以玫瑰冠类群鸡(玫瑰冠鸡)为材料,采用PCR-RFLP法检测了IGF-1基因5’调控区DNA序列多态性,并运用线性模型统计方法分析了多态性与初生重和12周龄体重的关系。
2.
Due to the importance of insulin-like growth factor-I in regulating many physiology and metabolic processes in animal body, so the IGF-I gene was chosen as a candidate gene to study important economic trait associated polymorphisms in chickens that made it more importance to scientific research.
胰岛素样生长因子-I(IGF-1)是动物体内重要的调节因子之一,因此,研究鸡的IGF-1基因多态性与其重要经济性状间的关系,使得IGF-1基因越来越受到重视,并被作为一个重要的候选基因进行研究。
4) IGF-1
IGF-1基因
1.
Correlation Analysis between Single Nucleotide Polymorphism of the IGF-1 Gene and Growth Traits in Yellow Chicken;
黄羽肉鸡IGF-1基因单核苷酸多态性与生长性状的相关研究
2.
Effects of IGF-1 gene polymorphism on egg-laying of Dehua black chicken
IGF-1基因多态性对德化黑鸡产蛋性状遗传效应的研究
3.
Gonadotropin-releasing hormone receptor(GNRHR) gene and insulin-like growh factor 1(IGF-1) gene which control the reproductive traits were studied as candidate genes on the Wenchang chicken(Chinese indigenous breed)in the present study.
以控制文昌鸡繁殖性状的促性腺激素释放激素受体基因(GNRHR)和胰岛素样生长因子-1基因(IGF-1)为候选基因,采用PCR-RFLP技术检测GNRHR基因和IGF-1基因在文昌鸡中的单核苷酸多态性(SNP),同时对这2个基因与文昌鸡繁殖性状的相关性进行了研究。
5) IGF-1 System
IGF-1通路
1.
The in Vitro Anti-cancer Effects of Curcumin and Its Influence on the IGF-1 System in Human Cancer Cell Lines;
姜黄素体外抗癌作用与IGF-1通路的关系及其机制研究
6) IGF-1 gene
IGF-1基因
1.
The first-generation (190) and the second-generation (244) were selected as experimental materials from Ⅱ type of new strain Huai pig,and PCR-RFLP methods were used for detecting gene polymorphisms with Hha Ⅰ restriction enzyme sites of IGF-1 gene and Rsa Ⅰ restriction enzyme site of Pit-1,then the correlation between gene polymorphisms and partial performances were analyzed.
以淮猪新品系Ⅱ系一世代(190头)、二世代(244头)为试验材料,采用PCR-RFLP方法分别检测IGF-1基因的HhaⅠ酶切位点、Pit-1基因的RsaⅠ酶切位点的多态性,并与生长性状进行相关性分析。
2.
Objective To investigate the expression of target genes and differentiation of adipose stromal cell(sADSCs)into chondrocytes by transfecting Sox-9 and/or igf-1 gene.
目的探讨应用Sox-9和igf-1基因转染大鼠脂肪干细胞(ADSCs)后,目的基因和蛋白分泌情况及向软骨细胞的分化效果。
补充资料：IGF
分子式：
CAS号：
性质：分子量7000的生长因子，IGF-I来源于成年的肝和其他部位平滑肌细胞，IGF-Ⅱ来源于胚胎肝、胎盘。靶细胞都是上皮细胞之间质细胞，刺激分化细胞的生长与修复，结构上约有50％的氨基酸序列与胰岛素同源，同时还与葡萄糖转运及代谢有关。也可用于Ⅱ型糖尿病的治疗。
CAS号：
性质：分子量7000的生长因子，IGF-I来源于成年的肝和其他部位平滑肌细胞，IGF-Ⅱ来源于胚胎肝、胎盘。靶细胞都是上皮细胞之间质细胞，刺激分化细胞的生长与修复，结构上约有50％的氨基酸序列与胰岛素同源，同时还与葡萄糖转运及代谢有关。也可用于Ⅱ型糖尿病的治疗。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条