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1)  IGF-1 chondrogenic
IGF-1软骨诱导
2)  Chondrocyte induction
软骨诱导
3)  cartilages
软骨向诱导
4)  Chondrocytic differentiation
软骨方向诱导
5)  Insulin-like growth factor 1
IGF-1
1.
Treatment and control skin tissue of sheep were sampled respectively for 0,3,6,9,12 and 50 days and the skin expression of growth hormone receptor(GHR),insulin-like growth factor 1(IGF-1),insulin-like growth factor receptor 1(IGF-1R),KAP3.
5mL(10ng/mL)的IGF-1,右侧肩胛部皮肤为未注射IGF-1的对照组,然后分别于第0、3、6、9、12、50d采集各皮肤样品,用反转录多聚酶链式反应(RT-PCR)方法,定量分析绵羊皮肤中生长激素受体(GHR)、胰岛素样生长因子1(IGF-1)和胰岛素样生长因子1型受体(IGF-1R)、角蛋白关联蛋白KAP3。
2.
Objective To investigate the roles of phosphatase and tensin homolog deleted on chromosome 10(PTEN),insulin-like growth factor 1(IGF-1),and insulin-like growth factor receptor 1 (IGF-1R) in the tumorigenesis,development,invasion and metastasis,and prognostic value of gastric cancer.
目的探讨PTEN、IGF-1、IGF-1R蛋白表达在胃癌发生、发展、侵袭转移及预后评价中的作用。
6)  Osteoinduction
诱导成骨
1.
Osteoinduction of CPPf/PLLA porous polymer adsorbing BMP 2/TGF β 1 in femoral head necrosis of rabbits;
复合多孔生物材料在股骨头坏死模型中诱导成骨的观察
2.
Experimental study on the ability of osteoinduction of allogeneic surface decalcified bone matrix gelatin;
同种异体表面脱钙骨基质明胶诱导成骨能力的实验研究
3.
Objective To observe the histological changes after BMP-2/TGF-β 1-adsorbed PLLA(poly-L-lactic acid)/CPPf(calcium polyphosphate fiber) porous polymer being infilled into the necrotic areas of femoral heads, and evaluate their activity of osteoinduction and biodegradation in order to search a new therapy for femur head necrosis(FHN).
目的 观察吸附有BMP 2和TGF β1的PLLA/CPPf多孔材料植入股骨头坏死 (Femurheadnecrosis ,FHN)病灶清除区后的组织学变化 ,评价其诱导成骨活性及生物降解性 ,以探索FHN治疗的新方法。
补充资料:IGF
分子式:
CAS号:

性质:分子量7000的生长因子,IGF-I来源于成年的肝和其他部位平滑肌细胞,IGF-Ⅱ来源于胚胎肝、胎盘。靶细胞都是上皮细胞之间质细胞,刺激分化细胞的生长与修复,结构上约有50%的氨基酸序列与胰岛素同源,同时还与葡萄糖转运及代谢有关。也可用于Ⅱ型糖尿病的治疗。

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