1) chromatin remodeling
染色质重构
1.
Chromatin remodeling plays an important role in DNA repair, gene transcriptional regulation.
染色质重构是DNA修复、基因表达调控过程中的一个重要环节。
2) chromatin remodeling
染色质重塑
1.
ATP dependent chromatin remodeling factors use the energy of ATP hydrolysis to introduce superhelical torsion into DNA and to alter the rotational phasing of the DNA on the surface of the histone octamer, thus to increase the accessibility of the nucleosomal DNA to transcription factors and restri.
染色质重塑是基因表达调控过程中一个非常重要的环节 。
2.
Thestudies in yeast and animal system had suggested that chromatin remodeling was required for the establishment andmaintenance of the expression pattern of the transcription factors, which played an important role in regulation ofgene expression.
多年来在酵母和动物等领域的研究已经证实,起关键调节作用的转录因子表达模式的建立和维持需要染色质重塑。
3.
The epigenetic regulation, such as genomic methylation, chromatin remodeling or histone deacetylation, has great influence on the maturation of CD4+T helper cells into Th1 phenotype or Th2 phenotype.
DNA甲基化、染色质重塑等表观遗传作用对CD4+T细胞向Th1和Th2的分化有重要的影响,现对Th1细胞表达IFN-γ以及Th2细胞表达IL-4／IL-13在基因转录水平的调节作用给予概述,重点阐述相关转录因子、酶以及蛋白质复合物所发挥的表观遗传调节作用的可能机制。
4) chromosome conformation
染色质构象
1.
Objective To establish chromosome conformation capture (3C) strategy and to use this method for exploring the effect of chromosome conformation on human α-globin gene expression in the human α-globin transgenic mouse.
目的用人珠蛋白转基因鼠模型建立染色质构象捕获的技术体系,探讨人α类珠蛋白基因簇的染色质构象变化与基因表达调控的关系。
5) chromatin organization
染色质构型
1.
According to chromatin organization, full growing mouse follicle oocytes were identified as SN-type, whose condensed chromatin surrounded nucleolus, or NSN-type, whose decondensed chromatin distributed in almost whole nuclear.
完全生长的小鼠卵泡卵根据染色质构型可分为两种类型，即SN型和NSN型。
6) Chromatin configuration
染色质构型
1.
The recovery of cumulus oocyte complexes(COCs),dynamics of meiosis and the relationship between COC morphology and GV chromatin configuration of porcine oocytes in pre ovulatory follicles were investigated at different time after hCG injection.
研究了超排处理注射 h CG后不同时间猪卵丘卵母细胞复合体 (COC)的回收率和形态、卵母细胞减数分裂进程以及 COC形态与生发泡 (GV)染色质构型之间的关系。
2.
Even though COCs were strictly selected before in vitro culture, the chromatin configuration of dictyate stage oocytes was different.
实验结果表明： 1 采用活体荧光染料Hoechst 33342对山羊生发泡进行观察，根据染色质构型及核仁大小将其分为8种形态：GV0、GV1、GV2(GV2-1、GV2-2)、GV3(GV3-1、GV3-2)GV4和GVBD。
3.
There are more evidence show that variouse stage of antral follicular oocyte before maturation culture in vitro, first reflected on the chromatin configuration of the nucleus , may account for the observed flaw of in vitro maturation system.
目前越来越多的证据表明，体外成熟培养前卵泡卵母细胞发育阶段的差异可能是卵母细胞体外成熟系统不完善的原因之一，这首先反映在未成熟卵母细胞核染色质构型就存在差别。
补充资料：X染色质
X染色质
生理名。亦 称Barr小体、X小体及巴氏小体。可见于人、哺乳类、鸟类、爬行类、两栖类及昆虫的雌体 细 胞核内。其在间期细胞核中，呈异固缩状态，染色深而密集。在显微镜下为一1～15μm之 浓染 小体。位置贴近核膜内面。具脱氧核糖核酸性质，对弗兰根反应阳性。用H·E染色、硫磺染 色均呈浓紫蓝色。用甲基绿-派朗宁混合剂可染成绿色。Guard的猩红快绿染色法染为红 色(常染色体呈绿色)。可作为人类性别鉴定及诊断性染色体异常的指标。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条