Chronopharmaceutical drug delivery system of theophylline and its pharmacokinetics in vivo;

OBJECTIVE To develop a chronopharmaceutical drug delivery system with biphasic (smow-fast) theophylline release for the nocturnal therapy of asthma,and study the mechanism of the biphasic theophylline release.

In the introduction of the topic mentioned above,this article strengthens the different grade of toxicities of anthracyclines resulted from its different usage The preliminary experience of 47 cases(73 chemotherapuetic cycles)who received doxorubicin of 96-hour infusion time schedule,circadian time schedule and their corresponding nursing care are discussed.

Guiding the Clinical Rational Use of Drugs Using Chronopharmacology;

Application of chitosan-based nanoparticles drug delivery system in ophthalmology;

A multiple-unit floating drug delivery system:research progress;

Application of novel preparation technigaes to drug delivery systems of polypeptides and proteins;

Preparation techniques and drug delivery systems of proteins and peptides in biomedicine;

The focal points of this paper are to introduce some new routes for drug administration, such as nasal, buccal and some new drug delivery systems (DDS) such as mucosal drug delivery systems, transdermal therapeutic system, controlled release drug.