1) Antisense oligodeoxynucleotide
反义寡脱氧核苷酸
1.
Reversal of multidrug resistance of breast carcinoma by antisense oligodeoxynucleotide combined with nanometer particle
纳米微粒介导反义寡脱氧核苷酸逆转乳腺癌细胞多药耐药的实验研究
2.
Inhibitory effect of c-erbB2 antisense oligodeoxynucleotide combined with taxol on proliferation of SK-Br-3 cells
c-erbB2反义寡脱氧核苷酸联合紫杉醇对乳腺癌细胞SK-Br-3的抑制作用
3.
Objective To investigate the inhibitory effect of heparanase antisense oligodeoxynucleotide (AS-ODN) on the invasiveness of human liver cancer cell lines SMMC-7721,BEL-7402 in vitro.
方法设计合成互补于HPAmRNA起始密码区的硫代反义寡脱氧核苷酸AS-ODN及相应的无义对照寡脱氧核苷酸NS-ODN,以阳离子脂质体OligofectamineTMReagent包埋后转染SMMC-7721、BEL-7402细胞。
2) Antisense oligodeoxynucleotides
反义寡脱氧核苷酸
1.
Objective To screen the antisense oligodeoxynucleotides (ASODN) that inhibit cultured hepatoblastoma HepG2 cell proliferation, and evaluate the antiproliferative potency of modified ASODN.
目的筛选对体外培养HepG2细胞抗增殖作用最强的反义寡脱氧核苷酸(anti-senseoligodeoxynucleotides,ASODN)序列,探讨经二次优化后该ASODN片段的抗增殖作用。
2.
Objective: To investigate the effects of c-jun on hCG-induced testosterone secretion in isolated rat Leydig cells by antisense oligodeoxynucleotides(ASODNs).
目的 :本研究拟通过c jun反义寡脱氧核苷酸 (ASODNs)观察c jun在调节hCG诱导的睾丸间质细胞 (LC)睾酮分泌中的作用。
3.
Hybridization in situ was used to detect proliferating cell nuclear antigen (PCNA) mRNA expression of BIU-87 cells which were treated with antisense oligodeoxynucleotides (ASODN) conjugated with lipofection.
运用原位杂交技术检测脂质体介导增殖细胞核抗原 ( PCNA)反义寡脱氧核苷酸抑制人膀胱癌细胞 BIU- 87PCNA m RNA的表达水平。
3) oligodeoxynucleotide antisense
反义寡脱氧核糖核苷酸
4) antisense oligodeoxynucleotide
反义寡聚脱氧核苷酸
1.
Inhibitory effect of antisense oligodeoxynucleotide targeting survivin on growth of human gastric cancer cells;
Survivin反义寡聚脱氧核苷酸对人胃癌细胞生长的抑制
5) antisense oligodeoxynucleotide
反义脱氧寡核苷酸
1.
Effect of MUC2 antisense oligodeoxynucleotideon on adherion and invasion ability of gastric cancer cells SGC7901 in vitro;
MUC2反义脱氧寡核苷酸对胃癌细胞体外黏附侵袭活性的影响
2.
The objective of study was to investigate the effect of liposomal transfection of antisense oligodeoxynucleotide (ASON) on alpha-globin gene expression and proliferation of K562 cells, to explore the new way of gene therapy in β-thalassemia.
本研究查明脂质体转染反义脱氧寡核苷酸(ASON)对K562细胞α珠蛋白基因表达的抑制作用及对细胞增殖的影响,探讨基因调控治疗β地中海贫血的新思路。
3.
To study the effect of VEGF fully phosporothioated antisense oligodeoxynucleotide (VEGF ASODN) on VEGF expression in acute monocyte leukemic cell line U937 in vitro, U937 cells were incubated with VEGF ASODN at concentrations of 10, 20 and 30 μmol/L or scrambled sequence as compared with negative control.
为研究硫代磷酸化修饰的血管内皮生长因子反义脱氧寡核苷酸 (VEGF ASODN)对急性单核细胞白血病细胞系U937VEGF表达的影响 ,将终浓度分别为 10 ,2 0 ,30 μmol/L的VEGF ASODN和错义序列与U937细胞分别孵育 2 4 ,4 8,72小时 ,采用RT PCR检测VEGFmRNA的表达 ,Westernblot检测VEGF蛋白的表达。
6) Smac/DIABLO antisense oligodeoxyonucleotide
Smac/DIABLO反义寡脱氧核苷酸
补充资料：脱氧核苷酸钠 ,脱氧核糖核苷酸钠
药物名称：脱氧核糖核苷酸钠
英文名：
别名： DNA单核苷酸钠;脱氧核苷酸钠 ,脱氧核糖核苷酸钠
适应症： 主要用于治疗急性白细胞减少症，对慢性白细胞减少症、再生障碍性贫血等也有一定疗效。
用量用法： 肌注：０．０５ｇ／次，１次／日，疗程不宜超过２～３周。冻干针剂临用前用等渗盐水或注射用水溶解。
规格： 针剂：０．０５ｇ／２ｍｌ；冻干针剂：０．０５ｇ。
类别：促进白细胞增生药
英文名：
别名： DNA单核苷酸钠;脱氧核苷酸钠 ,脱氧核糖核苷酸钠
适应症： 主要用于治疗急性白细胞减少症，对慢性白细胞减少症、再生障碍性贫血等也有一定疗效。
用量用法： 肌注：０．０５ｇ／次，１次／日，疗程不宜超过２～３周。冻干针剂临用前用等渗盐水或注射用水溶解。
规格： 针剂：０．０５ｇ／２ｍｌ；冻干针剂：０．０５ｇ。
类别：促进白细胞增生药
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条