1) proliferating cell nuclear antigen antisense oligodeoxynucleotide
增殖细胞核抗原反义寡脱氧核苷酸
1.
Objective:To study the time effect of low concentration proliferating cell nuclear antigen antisense oligodeoxynucleotide(PCNA-ASODN)on the expansion and differentiation of umbilical cord blood CD34+ hematopoietic precursor cells in vitro.
目的:探讨低浓度增殖细胞核抗原反义寡脱氧核苷酸(PCNA-ASODN)调节脐血造血前体细胞体外扩增和分化的时间效应。
2) oligodeoxynucleotide antisense
反义寡脱氧核糖核苷酸
3) antisense oligonucleotides or oligodeoxynucleotides
反义寡核苷酸或寡脱氧核苷酸
4) antisense oligodeoxynucleotide
反义寡聚脱氧核苷酸
1.
Inhibitory effect of antisense oligodeoxynucleotide targeting survivin on growth of human gastric cancer cells;
Survivin反义寡聚脱氧核苷酸对人胃癌细胞生长的抑制
5) Antisense oligodeoxynucleotide
反义寡脱氧核苷酸
1.
Reversal of multidrug resistance of breast carcinoma by antisense oligodeoxynucleotide combined with nanometer particle
纳米微粒介导反义寡脱氧核苷酸逆转乳腺癌细胞多药耐药的实验研究
2.
Inhibitory effect of c-erbB2 antisense oligodeoxynucleotide combined with taxol on proliferation of SK-Br-3 cells
c-erbB2反义寡脱氧核苷酸联合紫杉醇对乳腺癌细胞SK-Br-3的抑制作用
3.
Objective To investigate the inhibitory effect of heparanase antisense oligodeoxynucleotide (AS-ODN) on the invasiveness of human liver cancer cell lines SMMC-7721,BEL-7402 in vitro.
方法设计合成互补于HPAmRNA起始密码区的硫代反义寡脱氧核苷酸AS-ODN及相应的无义对照寡脱氧核苷酸NS-ODN,以阳离子脂质体OligofectamineTMReagent包埋后转染SMMC-7721、BEL-7402细胞。
6) Antisense oligodeoxynucleotides
反义寡脱氧核苷酸
1.
Objective To screen the antisense oligodeoxynucleotides (ASODN) that inhibit cultured hepatoblastoma HepG2 cell proliferation, and evaluate the antiproliferative potency of modified ASODN.
目的筛选对体外培养HepG2细胞抗增殖作用最强的反义寡脱氧核苷酸(anti-senseoligodeoxynucleotides,ASODN)序列,探讨经二次优化后该ASODN片段的抗增殖作用。
2.
Objective: To investigate the effects of c-jun on hCG-induced testosterone secretion in isolated rat Leydig cells by antisense oligodeoxynucleotides(ASODNs).
目的 :本研究拟通过c jun反义寡脱氧核苷酸 (ASODNs)观察c jun在调节hCG诱导的睾丸间质细胞 (LC)睾酮分泌中的作用。
3.
Hybridization in situ was used to detect proliferating cell nuclear antigen (PCNA) mRNA expression of BIU-87 cells which were treated with antisense oligodeoxynucleotides (ASODN) conjugated with lipofection.
运用原位杂交技术检测脂质体介导增殖细胞核抗原 ( PCNA)反义寡脱氧核苷酸抑制人膀胱癌细胞 BIU- 87PCNA m RNA的表达水平。
补充资料：增殖细胞核抗原
增殖细胞核抗原
PCNA是细胞DNA多聚酶的“δ”辅助蛋白，是真核细胞DNA合成时所必需的一种酸性核蛋白。PCNA在细胞核内合成，并储存在核内，细胞处于静止状态时，其含量很低，当细胞进入增殖周期中，其表达明显增加，故PCNA的表达高低可反映细胞增殖的活跃程度。在活检或手术切除的组织切片或细胞涂片上，用免疫技术检测到PCNA表达增高有助于肿瘤组织的诊断。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条