1) Homozygous deletion
纯合性缺失
1.
Detection of homozygous deletion and mutation of exon 5 and exon 8 of FHIT gene in differentiated thyroid carcinoma tissue;
分化型甲状腺癌组织中脆性组氨酸三联体基因外显子5、8纯合性缺失及突变检测
2.
The homozygous deletion was detectyed by multiple PCR analysis and mutation by PCR-SSCP and DNA sequencing followed.
方法采用多重PCR、PCR-SSCP和DNA测序对62例胃癌、癌旁组织及10例正常胃黏膜标本中p16INK4a基因纯合性缺失和突变进行检测。
3.
Aim: To investigate the frequencies of homozygous deletion of entire coding exons of fragile histidine triad (FHIT) gene in laryngeal squamous cell carcinoma (LSCC) tissue and its clinical significance.
目的:探讨喉鳞癌(LSCC)组织中脆性组氨酸三联体(FHIT)基因编码外显子纯合性缺失及其临床意义。
2) homozygous deletion
纯合缺失
1.
RESULTS: No homozygous deletion of p16 gene exon 1, 2 and 3 was observed in any of the 33 cases and no point mutation of p16 gene exon 2 was detected in 10 specimens.
结果:所有标本均未检出纯合缺失,10例标本进行了外显子2的序列测定,也未发现点突变。
2.
Methods: Polymerase chain reaction (PCR) and sequencing analysis were used to detect the homozygous deletion and point mutation of p16 gene in 84 cases of primary hepatocellular carcinomas and their adjacent liver tissues.
方法采用聚合酶链反应(PCR)和全自动序列分析的方法,研究84例肝癌和癌旁肝组织中pl6基因第1、2外显子纯合缺失和点突变的情况。
3.
The frequency of homozygous deletion was 8.
结果发现２例弥漫型胃癌有 ｐ１６基因的纯合缺失，缺失频率为８。
3) homozygous mutant gene
基因纯合缺失
4) homozygous deletions
纯合性丢失
5) loss of heterozygosity
杂合性缺失
1.
Identification of some macrosatillite sites of chromosome 19 in primary gastric carcinoma with loss of heterozygosity;
19号染色体微卫星杂合性缺失与原发性胃癌的临床关系
2.
Analysis of loss of heterozygosity in tk gene of L5178Y mouse lymphoma cells induced by colchicine and vincristine;
秋水仙碱和长春新碱诱导L5178Y小鼠淋巴瘤细胞tk基因杂合性缺失分析
3.
Study of loss of heterozygosity and microsatellite instabilities of fragile histidine triad gene in gastric carcinoma;
胃癌FHIT基因杂合性缺失及微卫星不稳定性的研究
6) LOH
杂合性缺失
1.
Study on 10q23 LOH and Both Mutation and Expression of PTEN Gene of the Oesophageal Squamous Cell Carcinomas in Chinese Population;
中国人食管癌10q23杂合性缺失和PTEN基因突变及表达研究
2.
Methods PCR-denaturing polyacrylamide gel electrophoresis-silver staining method was used to detect LOH of three mic- rusatellite locus located in the WWOX gene site of 31 breast cancer tissues.
目的检测乳腺癌组织中WWOX基因的杂合性缺失(LOH)状况及WWOX蛋白的表达状况,并探讨其与乳腺癌临床病理参数之间的关系。
3.
Objective:To detect the loss of heterozygosity(LOH) of ING1 gene microsatellite and the expression of p33ING1b protein in lung carcinoma and to investigate their association with the carcinogenesis of lung cancer.
目的:检测肺癌中抑癌基因ING1微卫星杂合性缺失(LOH)及其主要蛋白产物p33ING1b的表达情况,以探讨ING1基因改变与肺癌发生发展的关系。
补充资料：中枢性感觉缺失
中枢性感觉缺失
central anesthesia
脊髓或脑病变引起的感觉障碍。可分为传导束型(脊髓脑干损伤伤及感觉传导束）、丘脑型(丘脑痛）、内囊型(三偏症）和皮质型(单肢麻木）等不同类型。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条