Process Improvenment on the Synthesis of Sartanbiphenyl by Cross-coupling Reaction Using MnCl_2 as a Catalyst

2-Cyano-4 -methylbiphenyl(sartanbiphenyl) is a key intermediate of angiotensinⅡreceptor antagonists.

Study on the formulation of losartan potassium tablets;

Assay and test for related substances of Losartan potassium by HPLC;

Determination of two components in compound losartan potassium tablets by capillary zone electrophoresis;