Objective To investigate the contents of CD4+CD25+T cells and the expression of FoxP3 mRNA in these Treg cells in peripheral blood of the patients with gastric cancer and to characterize their clinical significance.

After the establishment of the model of ulcerative colitis by using trinitrobenzene sulfonic acid(TNBS)/ethanol method,the proportion of Treg cells and and CD4+T cells were detected by using flow cytometry analysis,at the same time,the expression of Foxp3 mRNA was measured in peripheral blood monocyte(PBMC)and.

CD4+CD25+ subset in peripheral blood and spleen lymphocytes was analyzed by flow cytometry;The level of Foxp3 mRNA was tested by RT-PCR;In vitro experiments were used to see if the supernatant medium of cultured leukemia cell line FBL3 could affect the proliferation of CD4+CD25+ Treg cells.

Experimental study of FOXP3 in the rat corneal allograft rejection;

Expression of mRNA and protein in the transcription factor Foxp3 in peripheral regulatory T cells of women with unexplained recurrent miscarriage;

Expression of FOXP3 and GITR/GITRL mRNA in peripheral blood monocytes of patients with rheumatoid arthritis and colorectal cancer;

Objective To investigate the percentages of CD4+CD25+ T cells in peripheral blood of patients with multiple sclerosis(MS),and the relation between clinical data and the expression of transcription factor forkhead box P3(FOXP3) in CD4+CD25+ T cells.

Objective: To investigate the effect of 1,25(OH)2 VitD3 on CD4+,CD25+ regulatory T cells and its specific transcription factor Foxp3 in rat spleen in Th1 immune reactioin.

Influence of Foxp3 gene-transferred CD4~+ CD25~- T cells on proliferation of allo T cells;

Objective: (1) To explore the relationship among CD4~+CD25~+ regulatory T cell, the level of IL-10 and TGF-β and the expression of FOXP3 mRNA levels of donor BM with GVHD in allogeneic hematopoietic stem cell transplantation(allo-HSCT).