1) Foxp3 gene
Foxp3基因
1.
Foxp3 gene expression in rat allograft liver transplantation tolerance model;
大鼠肝移植自然耐受模型移植术后Foxp3基因表达的变化
2.
Expression of CD4~+CD25~+ regulatory T cell and Foxp3 gene in systemic lupus erythematosus;
SLE患者CD4~+CD25~+调节性T细胞及Foxp3基因表达的研究
3.
Changes of number of regulatory T cells in peripheral blood and expression of Foxp3 gene in pemphigus vulgaris;
寻常型天疱疮患者外周血调节性T淋巴细胞数量及Foxp3基因表达
2) Foxp3
Foxp3基因
1.
Influence of Foxp3 gene-transferred CD4~+ CD25~- T cells on proliferation of allo T cells;
Foxp3基因转染小鼠CD4~+ CD25~- T细胞对同种T细胞增殖反应的影响
2.
Objective: (1) To explore the relationship among CD4~+CD25~+ regulatory T cell, the level of IL-10 and TGF-β and the expression of FOXP3 mRNA levels of donor BM with GVHD in allogeneic hematopoietic stem cell transplantation(allo-HSCT).
目的:(1)本研究应用免疫学、分子生物学方法结合临床资料来研究供体CD4~+CD25~+调控T细胞表达水平、移植后细胞因子IL-10、TGF-β的血浆水平以及供体FOXP3基因表达与GVHD的相关性。
3) Mouse Foxp3 gene
小鼠Foxp3基因
1.
Objective To clone Mouse Foxp3 gene(MFoxp3) and construct the prokaryotic expression vector of the protein,and to express and purify mouse Foxp3 fusion protein.
方法RT-PCR方法从小鼠淋巴细胞扩增出小鼠Foxp3基因,连入T Easy Vector进行测序,然后将序列正确的小鼠Foxp3基因用酶切的方法从T Easy vector切下,并将其连接到用相同酶切,含有硫氧还蛋白(含6个组氨酸“标签”)的pET 32a(+)原核表达载体中构建pET 32a(+)-MFoxp3表达载体。
4) forkhead transcription factor protein 3
转录因子FOXP3
1.
The aims of this study were to investigate the pathogenesis from immunological regulation level through analysis of CD4~+CD25~+ T regulatory cells (Tregs) and forkhead transcription factor protein 3 (FOXP3) in patients with PBC by means of flow cytometry, RT-PCR and immune suppression analysis.
本研究以CD4~+CD25~+免疫调节性T细胞(T regulatory cell,Tregs)及其相关转录因子FOXP3为中心,通过对我国PBC患者人群Tregs细胞定量检测及FOXP3的基因和蛋白表达的分析、FOXP3逆转录病毒载体的构建、体外诱导免疫调节性T细胞及细胞增殖抑制实验等一系列体外细胞实验,在免疫调节水平上进一步探讨该病的发病机制。
5) transcription factor Foxp3
Foxp3 转录因子
补充资料:J基因
分子式:
CAS号:
性质: 为免疫球蛋白V区与C区之间的连接区(J区)编码的基因。
CAS号:
性质: 为免疫球蛋白V区与C区之间的连接区(J区)编码的基因。
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