Objective: To analyze the numerical aberration of chromosome X, Y and 18 in the spermatozoa of asthenospermia patients by triple-color fluorescence in situ hybridization.

The clinical application of multicolor fluorescence in situ hybridization;

Methods A complex chromosomal rearrangement (CCR) invol ved in chromosomes 5, 16 and 20 in a 29-year-old male carrier was determined b y chro mosomal microdissection and multicolor fluorescence in situ hybridization(M -FIS H), and family degree investigation was further performed.

We elaborated a 47, XY, inv(9)(p11q13), +mar and a 46,XY,t(5;?) by combining a range of cytogenetic techniques, including multicolor fluorescence in situ hybridization (M-FISH), G-banding and NOR.

BACKGROUND & AIM: To investigate the difference of bone marrow chromosome aberrations induced by acute or chronic ionizing radiation with multicolor FISH (M-FISH) method.

In this study, multicolor FISH analysis on metaphase chromosomes of spinach with biotin-labeled 25S rDNA, DIG-labeled telomere sequences and biotin-labeled and DIG-labeled 5S rDNA was performed.

This study was aimed to establish the technique of multiplex fluorescence in situ hybridization (M-FISH) and to explore its usefulness in detection of complex chromosomal aberrations (CCAs) in acute lymphoblastic leukemia (ALL).

Detection of numerical aberrations of chromosomes 7 and 8 in sperms of workers exposed to benzene series by two-color fluorescence in situ hybridization;