1) Collagen-induced arthritis
胶原诱导的关节炎
1.
Effects of triptolide on expression of heat shock proteins and major hiscompatibility-Ⅰ molecule in synoviocytes and chondrocytes of collagen-induced arthritis rats;
雷公藤甲素对胶原诱导的关节炎大鼠关节局部热休克蛋白和主要组织相容性复合体Ⅰ类分子表达的影响
2.
AIM:To study the protective effects of human osteoprotegerin(OPG)-Mycobacterium tuberculosis heat shock protein 70(HSP70)fusion protein on animal models of the rheumatoid arthritis by the observation of the symptoms of collagen-induced arthritis(CIA)rats.
目的:研究人骨保护素(OPG)-分枝杆菌热休克蛋白70(HSP70)融合蛋白对类风湿关节炎动物模型——胶原诱导的关节炎(CIA)大鼠的保护性作用。
3.
Objective To detect the expression characteristics of IL-17 and TNF-α in collagen-induced arthritis(CIA) rats model.
目的探讨白细胞介素-17(interleukin-17,IL-17)、肿瘤坏死因子-α(tumour necrosis factor-α,TNF-α)在胶原诱导的关节炎(collagen-induced arthritis,CIA)大鼠模型的表达特点。
3) collagen induced arthritis
胶原诱导型关节炎
1.
The mechanism of immunosuppressive effect of sinominine on collagen induced arthritis of rat;
青藤碱对胶原诱导型关节炎免疫抑制作用的机制研究
2.
Objectives:To investigate the effect of genistein(gen) on IL-1β(interleukin-1β)、TNF-α(tumor necrosis factor-α)、VEGF(vascular endothelial growth factor) and MMPs(matrix metalloproteinases)(MMP-1、2、3、9) secreted by FLS(fibroblast-like synoviocytes) from rats with CIA(collagen induced arthritis).
目的:观察金雀异黄素(genistein, gen)对Ⅱ型胶原诱导型关节炎(collagen typeⅡinduced arthritis, CIA)大鼠关节成纤维样滑膜细胞(fibroblast-like synoviocytes, FLS)分泌的白细胞介素-1β(interleukin-1β, IL-1β)、肿瘤坏死因子-α(tumor necrosis factor-α, TNF-α)、血管内皮生长因子(vascular endothelial growth factor, VEGF)、基质金属蛋白酶-1、2、3、9(matrix metalloproteinase, MMP-1、2、3、9)的影响。
4) collagen Ⅱ-induced arthritis
Ⅱ型胶原诱导性关节炎
1.
Objective To study the effect of Guizhishaoyaozhimu Decoction(GSZD) on rats with collagen Ⅱ-induced arthritis(CIA) and to discuss the mechanism.
目的研究桂枝芍药知母汤对Ⅱ型胶原诱导性关节炎大鼠的治疗作用,并探讨其作用机制。
5) Collagen-induced arthritis
胶原诱导性关节炎
1.
Inhibition of sinomenine on nuclear factor-κB of synoviocytes in collagen-induced arthritis rats;
青藤碱对胶原诱导性关节炎大鼠滑膜细胞NF-κB的抑制作用
2.
OBJECTIE: To isolate and purify collagen typeⅡ(CⅡ) and establish the rat model of collagen-induced arthritis(CIA).
目的: 在鸡胸骨剑突软骨中提取、纯化Ⅱ型胶原蛋白(CⅡ)并进行初步鉴定,为制备胶原诱导性关节炎(CIA)大鼠模型提供原材料;制备CIA大鼠模型,从形态学、免疫学及病理组织学等多角度观察CIA大鼠模型特点;进一步阐明CIA大鼠的发病机制。
3.
Administration of recombinant or synthetic peptides containing CTE2 can improve the condition of collagen-induced arthritis(CIA) and reduce the anti-CⅡantibody level in serum and synovial fluid.
随后进一步的研究发现,CⅡ中真正发挥功能的区域是定位于CⅡ-CB11片段中260-270aa,称为CⅡ耐受原表位2(Collagen tolerogenic epitope 2,CTE2),单独给予包含该表位的化学合成或基因重组的多肽能够对胶原诱导性关节炎(Collagen-induced arthritis,CIA)症状起到缓解作用,并能显著降低血清及关节液中抗CⅡ抗体水平。
6) collagen induced arthritis
胶原诱导性关节炎
1.
The pathological effect of Qingbi tablet on synovium of rat with collagen induced arthritis;
清痹片对胶原诱导性关节炎大鼠滑膜组织病理学改变的影响
2.
Objective This study was performed to explore the interleukin( IL )-17 level in serum and expression in synovium, and to analyze the relationship with tumor necrosis factor-α(TNF-α) , joint destruction in the collagen induced arthritis (CIA) rat in different periods, so that we realize the effect of IL-17 on CIA and provide a new method of diagnosis and therapy for rheumatoid arthritis (RA).
目的探讨胶原诱导性关节炎(collagen induced arthritis CIA)大鼠不同时期血清IL-17水平及在滑膜组织的表达,及其与同期血清肿瘤坏死因子-α(TNF-α)和最终关节病理破坏的关系,研究IL-17在CIA发病中的作用机制,为类风湿关节炎的早期生物治疗提供线索。
补充资料：尿道炎-关节炎-结膜炎综合征
尿道炎-关节炎-结膜炎综合征
即“Reiter综合征”。多见于儿童。踝、膝关节易受累。可自愈，也可复发，发病期易与强直性脊柱炎及类风湿性关节炎混淆。治疗：休息，固定肢体，给止痛剂；有时需作滑膜切除术治疗慢性滑膜炎，足部关节有破坏时可考虑关节融合术。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条