1) collagen-induced arthritis
胶原性关节炎
1.
Regulatory effects of Paeoniflorin on G protein-coupled signaling of synoviocytes in collagen-induced arthritis rats;
芍药苷对胶原性关节炎大鼠滑膜细胞G蛋白偶联信号的调节作用
2.
Effects of tetramethylpyrazine on the expression of vascular endothelial growth factor in synovium of collagen-induced arthritis in rats;
川芎嗪对大鼠胶原性关节炎滑膜VEGF及VEGFmRNA表达的影响
3.
Effect of bizhongxiao decoction on the expression of 2-dimensional polyacrylamide gel electrophoresis protein in the synovial tissue with collagen-induced arthritis in rats;
痹肿消汤对胶原性关节炎大鼠滑膜双向电泳蛋白质表达的影响
2) Collagen induced arthritis
胶原性关节炎
1.
Objective To observe the influences of ligustrazine on the development of rat collagen induced arthritis(CIA) and vascular endothelial growth factor(VEGF).
目的观察川芎嗪对大鼠胶原性关节炎(CIA)炎症发展和滑膜分泌血管内皮生长因子(VEGF)的影响。
2.
AIM To investigate the prophylactic effects of the glucosides of cheanomeles speciosa (GCS) on the collagen induced arthritis (CIA) in mice and its relative immunological mechanisms.
目的 研究木瓜苷 (GCS)预防用药对小鼠胶原性关节炎 (collagen inducedarthritis,CIA)的影响 ,并探讨其初步机制。
3.
Objective: To explore the differences and mechanisms of two opposite approaches with heat or cold property chinese herbal formula in collagen induced arthritis (CIA) rats.
目的:从治疗作用评价、滑膜细胞超微结构观察的角度,探讨寒、热方剂清络饮、温络饮对胶原性关节炎大鼠的治疗作用、作用机理及作用异同。
3) collagen Ⅱ-induced arthritis
Ⅱ型胶原诱导性关节炎
1.
Objective To study the effect of Guizhishaoyaozhimu Decoction(GSZD) on rats with collagen Ⅱ-induced arthritis(CIA) and to discuss the mechanism.
目的研究桂枝芍药知母汤对Ⅱ型胶原诱导性关节炎大鼠的治疗作用,并探讨其作用机制。
4) Collagen-induced arthritis
胶原诱导性关节炎
1.
Inhibition of sinomenine on nuclear factor-κB of synoviocytes in collagen-induced arthritis rats;
青藤碱对胶原诱导性关节炎大鼠滑膜细胞NF-κB的抑制作用
2.
OBJECTIE: To isolate and purify collagen typeⅡ(CⅡ) and establish the rat model of collagen-induced arthritis(CIA).
目的: 在鸡胸骨剑突软骨中提取、纯化Ⅱ型胶原蛋白(CⅡ)并进行初步鉴定,为制备胶原诱导性关节炎(CIA)大鼠模型提供原材料;制备CIA大鼠模型,从形态学、免疫学及病理组织学等多角度观察CIA大鼠模型特点;进一步阐明CIA大鼠的发病机制。
3.
Administration of recombinant or synthetic peptides containing CTE2 can improve the condition of collagen-induced arthritis(CIA) and reduce the anti-CⅡantibody level in serum and synovial fluid.
随后进一步的研究发现,CⅡ中真正发挥功能的区域是定位于CⅡ-CB11片段中260-270aa,称为CⅡ耐受原表位2(Collagen tolerogenic epitope 2,CTE2),单独给予包含该表位的化学合成或基因重组的多肽能够对胶原诱导性关节炎(Collagen-induced arthritis,CIA)症状起到缓解作用,并能显著降低血清及关节液中抗CⅡ抗体水平。
5) collagen induced arthritis
胶原诱导性关节炎
1.
The pathological effect of Qingbi tablet on synovium of rat with collagen induced arthritis;
清痹片对胶原诱导性关节炎大鼠滑膜组织病理学改变的影响
2.
Objective This study was performed to explore the interleukin( IL )-17 level in serum and expression in synovium, and to analyze the relationship with tumor necrosis factor-α(TNF-α) , joint destruction in the collagen induced arthritis (CIA) rat in different periods, so that we realize the effect of IL-17 on CIA and provide a new method of diagnosis and therapy for rheumatoid arthritis (RA).
目的探讨胶原诱导性关节炎(collagen induced arthritis CIA)大鼠不同时期血清IL-17水平及在滑膜组织的表达,及其与同期血清肿瘤坏死因子-α(TNF-α)和最终关节病理破坏的关系,研究IL-17在CIA发病中的作用机制,为类风湿关节炎的早期生物治疗提供线索。
补充资料：尿道炎性关节炎
尿道炎性关节炎
病名。亦称Reiter综合征、Fiessinger-Leroy-Reiter综合征、Waelsch综合征、脓溢性特发性关节炎、性病性关节炎、结合膜尿道滑膜综合征、尿道-眼-关节(滑膜)综合征。许多病原体被认为与之有关，如类胸膜炎菌、衣原体、福氏痢疾杆 菌(肠型者)。自身免疫，皮肤病变类似脓疱性牛皮癣，过度角化症，海绵状脓疱。滑膜改变 为非特异性，后期似类风湿性关节炎的损害。男性多见，11～40岁发病。尿道炎：出现最早 ，可能不被注意，也可为严重的痛性排尿、血尿、脓尿。在肠型者尿道炎常轻微。后期发生 环状龟头炎。结合膜炎(50%以上)：在尿道炎开始后10日出现，从轻度充血到化脓性病变， 很少同时有虹膜炎、角膜炎。关节炎(最常见)：对称性，常累及膝、踝、跖及跗关节，很少 为腕关节。关节周围肿胀、皮肤苍白、变热，关节痛，轻度发热，有些病例以腹泻为首发症 状，在2～3周或数年后才相继或同时出现上述“三联症状”，但表现较轻。在患关节炎的同 时或以后发生局部或全身皮肤角化症，口腔黏膜损害。急性期可有血沉加快，X线示早期骨 质疏松、软组织肿胀，后期皮肤侵蚀，新骨形成，关节破坏。治疗用四环素、保泰松、肾上 腺皮质激素，亦可理疗。部分自发缓解，反复发作可引起关节强直。并发症有心肌炎、心包 炎、胸膜炎、主动脉瓣损害、心传导阻滞、肺浸润、青光眼和血栓性静脉炎。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条