1) dynorphin
强啡肽
1.
Effect of N-nitro-L-arginine on the Inhibition of Morphine Physical Dependence in Rats and Its Dynorphin A Mechanism;
N-硝基-L-精氨酸抑制大鼠吗啡身体依赖的强啡肽机制
2.
Changes of extracellular adenosine concentration in spinal cord in dynorphin-induced paralysis rats;
强啡肽A致截瘫大鼠脊髓组织细胞外腺苷浓度的变化
3.
Research on mechanism of non-opioid receptor in dynorphin-induced spinal cord injury;
强啡肽致脊髓损伤中非阿片样受体机制的研究
2) prodynorphin
前强啡肽
1.
) application antisense oligodeoxynucleotide (AS-ODN) to induce prodynorphin (Pro-Dyn) mRNA and observed the degree of inflammatory edema after the formalin injection in rats to prove whether the quantity of dynorphin A in nerve centre could effect the degree of periphery inflammation.
目的:利用鞘内注射前强啡肽mRNA的反义寡聚核苷酸,观察由福尔马林引起的大鼠后脚炎性水肿程度的变化,来证明脊髓背角中强啡肽(dynorphin,Dyn)A的量可能影响外周炎症反应的大小。
2.
Total RNA in hippocampus was extracted and primers of enkaphalin or prodynorphin were respectively added for RT-PCR reaction.
方法:采用单纯束缚的方法建立慢性束缚性应激的大鼠模型,提取海马总RNA,采用RT-PCR反应扩增脑啡肽和前强啡肽基因,比较二者在海马中的表达情况。
3.
Aim: To investigate the changes of enkaphalin mRNA and prodynorphin mRNA gene expression in rat brain regions with chro-(nic) immobilization stress and the influence of Chinese herbs.
目的:研究慢性束缚应激时大鼠海马脑啡肽和前强啡肽mRNA基因表达的变化以及逍遥散、四君子汤、金匮肾气丸三种中药复方对其的影响。
3) dynorphin A
强啡肽A
1.
Up-expression of dynorphin A aggravates inflammatory edema induced by formalin test in rats;
脊髓背角中强啡肽A表达的上调对福尔马林引起的大鼠炎性水肿的影响
2.
Methods: Twenty patients of lumbar intervertebral disk prolapse were treated by extradural injection of Mailuoning, the spontaneous release of dynorphin A (Dyn A) in cerebrospinal fluid (CSF) before and after treatment were measured and compared with that of the 20 cases in the control group to determine the therapeutic effect of Mailuoning.
方法 :用硬膜外注射中药脉络宁的方法治疗腰椎间盘突出症患者 (实验组 ) 2 0例 ,设对照组 2 0例 ,并观察两组患者治疗前后脑脊液中强啡肽A(Dyn A)的自发释放趋势 ,以判定其疗效。
3.
Objective:To investigate the effects of progesterone on morphine rewarding effect and levels of dynorphin A (DynA) in rat brain.
目的:观察孕酮对于吗啡所致奖赏效应及相关脑区中强啡肽A水平的影响。
4) dynorphins
强啡肽类
5) prodynorphin
强啡肽原
1.
Objective: To observe the effect of chronic levodopa (L dopa) administration on striatal prodynorphin mRNA expression in a rat model of Parkinson disease (PD), and probe into the pathogenesis of L dopa induced dyskinesias (LID).
目的 :观察左旋多巴 (L dopa)治疗对帕金森病 (PD )大鼠纹状体强啡肽原表达的影响 ,探讨L dopa诱发异动症 (LID)的机制。
2.
Objective:To investigate the relationship between the Prodynorphin gene and the dopamine D_2 receptor gene and the susceptibility of schizophrenia in Chinese Han population and explore the effect of interaction of the two genes on the presence of schizophrenia.
目的:探讨中国汉族人群强啡肽原(Prodynorphin,PDYN)基因和多巴胺D_2受体(dopamine D_2 receptor,DRD_2)基因与精神分裂症遗传易感性的关系及其相互作用对精神分裂症的影响。
6) dynorphin B
强啡肽B
补充资料：强啡肽
分子式：
CAS号：
性质：具有强镇痛效应的一种内源性神经肽。从猪垂体分离得到由256个氨基酸组成的脑啡肽原B（强啡肽/新内啡肽原），其C端经酶解可得到4种强啡肽：（1）强啡肽A（209～225），十七肽，其效力比亮氨酸脑啡肽强700倍，比内啡肽强50倍；（2）强啡肽B（228～240），十三肽；（3）强啡肽32（209～240），32肽，含强啡肽A和B；（4）强啡肽1～8（209～216）八肽。这4长期共存中强啡肽的N端都含有亮氨酸脑啡肽的氨基酸序列（Tyr-Gly-Gly-Phe-Leu）。
CAS号：
性质：具有强镇痛效应的一种内源性神经肽。从猪垂体分离得到由256个氨基酸组成的脑啡肽原B（强啡肽/新内啡肽原），其C端经酶解可得到4种强啡肽：（1）强啡肽A（209～225），十七肽，其效力比亮氨酸脑啡肽强700倍，比内啡肽强50倍；（2）强啡肽B（228～240），十三肽；（3）强啡肽32（209～240），32肽，含强啡肽A和B；（4）强啡肽1～8（209～216）八肽。这4长期共存中强啡肽的N端都含有亮氨酸脑啡肽的氨基酸序列（Tyr-Gly-Gly-Phe-Leu）。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条