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1)  Osteoinduction
诱导成骨
1.
Osteoinduction of CPPf/PLLA porous polymer adsorbing BMP 2/TGF β 1 in femoral head necrosis of rabbits;
复合多孔生物材料在股骨头坏死模型中诱导成骨的观察
2.
Experimental study on the ability of osteoinduction of allogeneic surface decalcified bone matrix gelatin;
同种异体表面脱钙骨基质明胶诱导成骨能力的实验研究
3.
Objective To observe the histological changes after BMP-2/TGF-β 1-adsorbed PLLA(poly-L-lactic acid)/CPPf(calcium polyphosphate fiber) porous polymer being infilled into the necrotic areas of femoral heads, and evaluate their activity of osteoinduction and biodegradation in order to search a new therapy for femur head necrosis(FHN).
目的 观察吸附有BMP 2和TGF β1的PLLA/CPPf多孔材料植入股骨头坏死 (Femurheadnecrosis ,FHN)病灶清除区后的组织学变化 ,评价其诱导成骨活性及生物降解性 ,以探索FHN治疗的新方法。
2)  Osteoinductive
诱导成骨
1.
Objectives:To explore the osteoinductive capability of the human acellular amniotic membrane(HAAM) in lumbar vertebra of mature canine,to provides the basis of HAAM as the bone tissue engineering natural occurring matrix,and provides a new treatment idea for the treatment of bone defects and vertebral fusion.
目的:初步探讨人完全脱细胞羊膜(human acellular amniotic membrane,HAAM)的在犬椎体的诱导成骨的能力,为羊膜作为骨组织工程自然衍发基质提供实验依据,进而为骨缺损及椎体融合术提供新的治疗思路。
3)  Induced osteogenesis
诱导成骨
1.
Objective To observe CTLA-4Ig protein expression in human marrow mesenchymal stem cells(hMSCs)transfected with adenovirus-mediated CTLA-4Ig gene and the effect of gene modification on hMSCs induced osteogenesis.
目的通过腺病毒介导CTLA-4Ig基因转染人骨髓间充质干细胞(human marrowmesenchymal stem cells,hM-SCs),观察被修饰细胞CTLA-4Ig蛋白表达情况,以及基因修饰对hMSCs诱导成骨特性的影响。
4)  Inductive osteogenesis
诱导成骨
5)  Bone formation
诱导成骨
6)  osteogenic induction
成骨诱导
1.
Osteogenic induction of rabbit s bone marrow stromal cells and transfection of AAV-EGFP in vitro;
兔骨髓基质干细胞成骨诱导及增强型绿色荧光蛋白基因腺相关病毒体外转染的研究
补充资料:成骨细胞

  
  成骨细胞
  

  成骨细胞是骨的形成、骨骼发育与生长的重要细胞,其体积较大,呈立方形或矮柱状,胞浆较丰富,呈强嗜碱性。核大而圆,常位于胞体的一侧,核仁清晰可见。成骨细胞内富于核糖核酸,PAS染色呈阳性反应;碱性磷酸酶染色呈强阳性。成骨细胞可向其周围生生胶原纤维及基质,在未钙化前称为类骨质。类骨质的微纤维间彼此侧向融合,骨盐结晶逐渐沉积,最后类骨质区完全骨质化。成骨细胞在分泌类骨质的过程中逐渐被埋于其中并转变成骨细胞。成骨细胞还能形成基质小泡,其内含有大量的碱性磷酸酶、类脂及小的钙盐结晶体。基质小泡破裂后,碱性磷酸酶能使局部磷酸含量增高。磷脂与钙有很强的亲和力,可使钙盐结晶成为钙化核心,并使钙化范围逐渐扩大,从而导致类骨质的迅速钙化。
  
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