Synthesis and hypoglycemic activity of sulfonaminothioureas and sulfonamino-cyanoguanidines;

Synthesis of N-(3-Phenyl-2,3,4-triazole formyl)-N′-acylthiosemicarbazides;

A new derivative of acylthiosemicarbazide——N-naphthoacetyl-N′-o-methoxybenzoyl thiosemicarbazide was synthesized by the addition reaction of α-naphthoacetyl isothiocyanate with arylhydrazine,whose structure was confirmed by IR spectra,1HNMR,13CNMR and elemental analysis.

Acylthiosemicarbazide (Ⅲa～Ⅲd) were prepared by reaction of 2-trifluoromethyl benzimidazole-1-acetyl hydrazine(1) with aryl isothiocyanate in the presence of anhydrous ethanol.

Studies on the Acylthiosemicarbazides and the Related Heterocyclie Derivatives ⅩⅩⅣ.Synthesis of 5-(2,4-Dichlorophenoxymethylene)-2-aroylamino-1,3,4-thiadiazoles;

Eight novel triazinyl phenylthiomethanesulfonyl ureas (2,3) were prepared by reacting phenylthiomethanesulfonamides (1) with 4,6- dichloro - 2 - triazinyl isocyanate using potassium carbonate as catalyst, and then treated further with sodium methoxide in methanol.