1) gamma-secretase inhibitor
γ泌肽酶抑制剂
1.
Objective To explore the inhitition effect of gamma-secretase inhibitor on Notch signaling molecules in alveolar epithelial type Ⅱ cell(AEC Ⅱ) in a heterocellular culture of AECⅡ and lung fibroblast(LF).
目的探讨γ泌肽酶抑制剂在肺泡Ⅱ型上皮细胞(AECⅡ)与肺成纤维细胞(LF)共培养胎鼠模型中对Notch信号分子表达的影响。
2) γ-secretase inhibitors
γ-分泌酶抑制剂
1.
Research on Computer-Aided Drug Design, Synthesis and Initial Activity Evaluation of γ-Secretase Inhibitors with Neuroprotective Effect;
兼有神经保护作用的γ-分泌酶抑制剂的计算机辅助设计、合成及初步活性实验研究
2.
Methods A series of compounds were designed,synthesized,and evaluated based on pharmacophore model of γ-secretase inhibitors by virtual screening in MDL.
目的通过在数据库中虚拟筛选,以期发现新的γ-分泌酶抑制剂。
3) γ-secretase inhibitor
γ分泌酶抑制剂
1.
SectionⅠ: The expression and activation of Notch signaling in human breast cancer and the effect ofγ-secretase inhibitor on the proliferation of breast cancer Background: Notch signaling is a pathway highly conserved through evolution which regulates various physiological processes,including stem cell maintenance, differentiation,proliferation and apoptosis.
第一部分乳腺癌标本及乳腺细胞系中Notch信号通路的表达、活化及γ分泌酶抑制剂对乳腺癌细胞增殖的影响 研究背景: Notch信号传导通路是在进化过程中高度保守的信号传导系统,由Notch受体和配体组成。
4) DAPT
γ-分泌酶抑制剂DAPT
1.
γ-secretase inhibitor DAPT suppresses the proliferation of Jurkat T cells
γ-分泌酶抑制剂DAPT抑制Jurkat T细胞增殖
6) secretase inhibitor
分泌酶抑制剂
1.
00 μg·mL~(-1)),β-secretase inhibitor(S4562,100.
mL-1)、β分泌酶抑制剂(S4562,100。
补充资料：羧肽酶抑制剂
分子式：
CAS号：
性质：抑制羧肽酶(EC3.4.17)活性的化合物。羧肽酶是一种羧肽端解酶，催化氨基酸从肽链C-末端水解。羧肽酶A催化大多数的氨基酸水解，使肽链从C-末端依顺序降解；羧肽酶B只能催化C-末端赖氨酸或C-末端精氨酸的水解。羧肽酶抑制剂，如苄基苹果酸、组精素等在临床上可用以提高迟发型超敏反应。
CAS号：
性质：抑制羧肽酶(EC3.4.17)活性的化合物。羧肽酶是一种羧肽端解酶，催化氨基酸从肽链C-末端水解。羧肽酶A催化大多数的氨基酸水解，使肽链从C-末端依顺序降解；羧肽酶B只能催化C-末端赖氨酸或C-末端精氨酸的水解。羧肽酶抑制剂，如苄基苹果酸、组精素等在临床上可用以提高迟发型超敏反应。
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参考词条