Phoslactomycins,named after the phosphate group and amino-group in the moleculars,are a class of polyketide antifungal and antitumor antibiotics produced by many Streptomyces.

Polyketides and combinatorial biosynthetic approaches;

The production of polyketides in heterologous hosts offers many advantages over the use of natural producers.

Since the recurrence of the known polyketides is very high during the discovery of novel natural polyketide compounds using traditional methods, new approaches are developed for the biosynthesis of these compounds,.