1) receptor agonists
受体激动剂
1.
Purpose To build a three dimensional structure activity relationship model of the title compounds and gain further insights into requirements for potential nonsteroidal progesterone receptor agonists.
目的 建立非甾体类孕酮受体激动剂5-亚苄基-1,2-二氢-5H-苯并吡喃并[3,4-f]喹啉衍生物的三维 定量构效模型,为设计高效的非甾体类孕酮受体激动剂提供理论依据。
2) M1 receptor agonist
M1受体激动剂
1.
3-(3-Chloro-1,2,5-thiadiazol-4-yl)pyridine,which is a key intermediate of selective M1 receptor agonist xanomeline,was synthesized from 3-pyridine carboxaldehyde,sodium cyanide,and sulfur chloride.
以3-吡啶甲醛为原料,与氰化钠、一氯化硫反应合成选择性M1受体激动剂占诺美林的关键中间体3-(3-氯-1,2,5-噻二唑-4-基)吡啶,目标化合物的结构经1H-NMR谱确证。
2.
In this paper, the recent research progress in drugs for treatment of AD and their mechanisms are reviewed, including AChE inhibitor,M1 receptor agonist,antioxidants,nerve growth factor,calcium regulator and so on.
综述了近5年来治疗AD药物的研究进展,根据作用机制的不同对临床应用的抗AD和有促智活性的药物进行分类详述,主要分为乙酰胆碱酯酶抑制剂等改善胆碱功能的药物、M1受体激动剂、抗氧化药物、消炎镇痛药物、抑制Aβ蛋白形成的药物、神经生长因子、钙调节剂、晚期糖基化终产物(AGE)抑制剂以及中药复方等几类。
3) β2-agonists
β2-受体激动剂
1.
The method for determination of β2-agonists (salbutamol, terbutaline, cimaterol, cimbuterol, ractompamine, clenbuterol, bromobuterol, isoxsuprine, mabuterol, mapenterol, bromclenbuterol) residues in liver and meat of pig was developed by HPLC/MS-MS.
建立了同时检测11种β2-受体激动剂物质(包括沙丁胺醇、特布它林、塞曼特罗、塞布特罗、莱克多巴胺、克仑特罗、溴布特罗、苯氧丙酚胺、马布特罗、马贲特罗、溴代克仑特罗)在猪肉及猪肝脏中残留量的液相色谱-串联质谱(HPLC/MS-MS)方法。
2.
A delicate method has been developed for the simultaneous determination of 23 β2-agonists and 5 β-blockers illegal drugs in muscle tissues by high performance liquid chromatography-linear ion trap mass spectrometry using isotope dilution technique.
利用高效液相色谱-线性离子阱质谱(HPLC-ITMS)以同位素稀释技术测定了肌肉组织中23种β2-受体激动剂及5种β-阻断剂。
4) β-agonists
β-受体激动剂
1.
Determination of β-agonists in Pig Urine by HPLC-MS/MS;
高效液相色谱-串联质谱法检测猪尿中四种β-受体激动剂残留的研究
2.
A reasonable and reproducible liquid chromatography-mass spectrometry(LC/MS) for detecting β-agonists was developed.
建立了合理、可靠的液相色谱-质谱联用测定β-受体激动剂的方法。
3.
The separation ofβ-agonists was performed.
建立了动物源食品中特布他林、西马特罗、沙丁胺醇、非诺特罗、氯丙那林、莱克多巴胺、克仑特罗、妥布特罗和喷布特罗等9种β-受体激动剂残留检测的超高效液相色谱-串联质谱方法。
5) 5-HT4 receptor partial agonist
5-HT4受体激动剂
6) Selective AT2 receptor agonist
AT2受体激动剂
补充资料：受体激动剂
受体激动剂
receptor activating age?nts
能与受体结合，且可使受体激动，从而表现出相应的生理效应或药理作用的药物。例如乙酰胆碱，可与M胆碱受体结合，并使之激动，产生腺体分泌增加，心率减慢、血管扩张、支气管及胃肠道平滑肌收缩和瞳孔缩小等效应。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条