1) human telomerase reverse transcriptase
hTERT
1.
Expression of human telomerase reverse transcriptase in gastric adenocarcinoma;
hTERT蛋白在胃腺癌组织中定量表达的研究
2.
Functional changes of dendritic cells after infection by recombinant retrovirus carrying human telomerase reverse transcriptase gene fragment;
含hTERT片段的重组逆转录病毒感染对树突状细胞功能的影响
3.
Objective:To observe the effect of shRNA by targerting human telomerase reverse transcriptase (hTERT) mRNA in the human mesenchymal stem cells(hMSCs)lines and explore the safety of RNAi by targerting hTERT mRNA in clinical application.
目的:观察靶向人端粒酶逆转录酶(hTERT)的短发夹RNA(shRNA)对人骨髓间充质干细胞(hMSCs)生长增殖的影响,探讨靶向hTERT的RNA干扰技术临床应用的安全性。
2) telomeric repeated binding factor 2(TRF_2)
hTERT TRF_2
3) hTERT promoter
hTERT启动子
1.
Changes of biological character of SKOV3 cells transfected with HSV-tk gene under the control of hTERT promoter;
hTERT启动子调控的HSV-tk基因逆转录病毒载体的构建及SKOV3转染细胞的生物学特性观察
2.
Aim: To investigate the effect of ganciclovir and topotecan on SKOV3 cell transfected HSV tk under the control of hTERT promoter.
目的 :探讨更昔洛韦 (GCV)与拓扑替康 (TPT)单独或联合应用对携带有hTERT启动子调控的HSV tk基因的SKOV3细胞生长的影响。
3.
METHODS: The hTERT promoter and TK gene were cloned, andwhich was connected to the PGL3 carrier after enzyme digestion, toconstruct the hTERTp/PGL3、TK/PGL3、hTERTp/TK/PGL3 recombinantcarriers, and then to construct the CMV/TK/PGL3 recombinant carrierswith the similar method and regard CMV a.
方法：克隆hTERT启动子及TK基因，酶切后连接到pGL3载体上，构建hTERTp／pGL3，TK／pGL3，hTERTp／TK／pGL3重组载体。
4) hTERT
hTERT基因
1.
Telomerase activity and expression of hTERT gene are sentive to the apoptosis indusied by carboplatin in human ovarian cancer cells;
卡铂诱导卵巢癌细胞凋亡与端粒酶活性、hTERT基因表达改变的关系
2.
Inhibition of the expression of hTERT gene in nasopharyngeal carcinoma cells by small interfering RNA;
小干扰RNA抑制鼻咽癌细胞hTERT基因表达的实验研究
3.
To explore whether overexpression of human telomerase reverse transcriptase (hTERT) in Raji cells can prevent etoposide-induced apoptosis.
采用脂质体介导的转染方法将重组的hTERT基因转入Raji细胞 ,G4 18筛选 ;采用间接免疫荧光标记法及端粒酶聚合酶链反应 酶联免疫测定法检测hTERT蛋白表达水平和端粒酶活性的变化 ;姬姆萨染色及流式细胞仪观测细胞凋亡。
5) hTERT gene
hTERT基因
1.
Effects of As_2O_3 on hTERT gene expression and telomerase activity in HL-60 cells;
三氧化二砷对HL-60细胞hTERT基因表达和端粒酶活性的影响
2.
Effects of all-trans retinoic acid on hTERT gene expression and telomerase activity in HL-60 cells;
全反式维甲酸对HL-60细胞hTERT基因表达和端粒酶活性的影响
3.
Effect of hTERT gene silencing by RNA interference on proliferation and apoptosis of human breast cancer cells;
siRNA沉默hTERT基因表达对人乳腺癌细胞增殖和凋亡的影响
6) hTERT
端粒酶hTERT
1.
Expression and significance of hTERT,p16 and Topo-Ⅱa in astrocytoma by tissue microarray;
利用组织芯片研究星形细胞瘤中端粒酶hTERT,p16及Topo-Ⅱa的表达及意义
2.
ObjectiveTo explore the possibility that the expression level of hTERT(human telomerase reverse transcriptase) can be used to diagnose lung carcinoma,we analyse the relationship of lung carcinoma with the expression level of hTERT by quantifying the expression level of hTERT in lung carcinoma tissue.
目的通过定量检测肺癌组织端粒酶hTERT的表达水平,分析肺癌与hTERT表达的定量关系,为从hTERT的表达方面探讨肺癌的诊断问题提供实验依据。
补充资料：TRF
分子式：
CAS号：
性质：又称促甲状腺素释放激素。由丘脑下部提取或人工合成制得。三肽，易溶于无水甲醇，略溶于氯仿，不溶于吡啶。TRF是下丘脑所分泌的激素释放因子之一，下丘脑只含TRH总量的31%，实际上除小脑外，脑的各部分都存在TRH。TRH不仅调节垂体前叶释放促甲状腺激素，也促进生长激素和催乳激素的释放。垂体和甲状腺功能诊断试剂，也用于治疗甲状腺功能减退和甲状腺癌。
CAS号：
性质：又称促甲状腺素释放激素。由丘脑下部提取或人工合成制得。三肽，易溶于无水甲醇，略溶于氯仿，不溶于吡啶。TRF是下丘脑所分泌的激素释放因子之一，下丘脑只含TRH总量的31%，实际上除小脑外，脑的各部分都存在TRH。TRH不仅调节垂体前叶释放促甲状腺激素，也促进生长激素和催乳激素的释放。垂体和甲状腺功能诊断试剂，也用于治疗甲状腺功能减退和甲状腺癌。
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参考词条