1) Tyrosine kinase
酪氨酸激酶
1.
Effect of PDT on the activity of protein tyrosine kinase and phosphatase in H22 cells;
光动力疗法对H22细胞蛋白酪氨酸激酶及磷酸酶活性的影响
2.
Effects and mechanisms of epidermal growth factor receptor of tyrosine kinase on cancer;
表皮生长因子受体酪氨酸激酶抑制剂BPI-2009的抗肿瘤作用及其机制的研究
3.
Expression, purification and bioactivity determination of epidermal growth factor receptor protein tyrosine kinase;
表皮生长因子受体蛋白酪氨酸激酶的表达、纯化及活性测定
2) protein tyrosine kinase
酪氨酸激酶
1.
This paper reviewed recent progresses in the pharmacotherapeu- ties and clinical studies of the molecular-targeted anti-tumor drugs,including topoisomerase inhibitor, protein tyrosine kinase inhibitor,tumor angiogenesis inhibitor,PI3K-AKT-mTOR inhibitor and cyclin-de- pendent kinase inhib.
笔者综述了近年来DNA拓扑异构酶抑制剂、蛋白酪氨酸激酶抑制剂、肿瘤新生血管生成抑制剂、磷脂酰肌醇-3激酶/蛋白激酶B/哺乳动物雷帕霉素靶体(PI3K-AKT-mTOR)信号通路抑制剂、细胞周期依赖性蛋白激酶抑制剂的临床应用和临床研究进展。
3) Tyrosine kinase A
酪氨酸激酶A
1.
Objective To observe the changes of tyrosine kinase A(TrkA) in different cerebral regions of ovariectomized rats.
目的观察卵巢切除大鼠脑内不同部位酪氨酸激酶A(TrkA)表达的变化。
4) TrkA
酪氨酸激酶A
1.
Objective To investigate the expression of tyrosine kinase A(TrkA) in cerebral cortex neural stem cells of embryonic rats,so to find the functions of TrkA and demonstrate the possible mechanism of neural stem cells directional differentiation during the development of the nervous system.
目的通过研究不同发育阶段大鼠大脑皮层神经干细胞上TrkA(酪氨酸激酶A)表达的改变,为了解Tr-kA在神经系统发育中的作用与神经干细胞定向分化的可能机制打下基础。
2.
Objective To study the expressions of tyrosine kinase A (TrkA) and nerve growth factor (NGF) on cochlear corti in rats after whole cerebral ischemia-reperfusion.
目的探讨大鼠全脑缺血再灌注后酪氨酸激酶A(TrkA)和神经生长因子(NGF)在耳蜗Corti器的表达。
3.
The expression of NGF and TrkA mRNA/protein were measured with methods of RT-PCR and immunohistochemistry respectively at 2,4,6,12h and 24h after reperfusion in cerebral cortex ofrats.
目的探讨注射用血塞通对局灶性脑缺血再灌注神经生长因子(NGF)及酪氨酸激酶A(TrkA)含量变化的影响,并观察其对缺血性脑损伤的神经元保护作用。
5) Tyrosine protein kinase
酪氨酸蛋白激酶
1.
Relationship between tyrosine protein kinase and synapse plasticity, learning and memory;
酪氨酸蛋白激酶与突触可塑性及学习记忆的关系
2.
· AIM: To study the function of tyrosine protein kinase pathway in ultraviolet induced enhanced PGE2 synthesis in human lens epithelial cells (HLECs).
目的:探讨酪氨酸蛋白激酶途径在紫外线引起的晶状体上皮细胞前列腺素E(2PGE2)合成增加过程中的作用。
3.
Objective: To examine the effect of basic fibroblast growth factor (bFGF) of different concentrations on activitites of tyrosine protein kinase (TPK), protein kinase C(PKC) and extracellular signal regulated protein kinase (ERK) in NIH3T3 cell line and to elucidate the signal pathway in cell proliferation and differentiation.
目的 :观察碱性成纤维细胞生长因子 (bFGF)对NIH3T3细胞酪氨酸蛋白激酶 (TPK)、蛋白激酶C(PKC)及胞外调节蛋白激酶 (ERK)活性的影响 ,探讨其信号转导机制。
6) Receptor tyrosine kinase
受体酪氨酸激酶
1.
Expression and its clinical significance of receptor tyrosine kinase EphB1 in gastric carcinoma
受体酪氨酸激酶EphB1在胃癌中的表达及其临床意义
2.
Mer is one member of Axl receptor tyrosine kinase family, and its ligand Gas6 can stimulate activity of Mer receptor tyrosine kinase after binding it, and then activate the downstream signal transduction pathway, Mer participates in cell inflammation, apoptosis, tumorigenesis, thrombosis and hemostasis.
Mer是Axl受体酪氨酸激酶家族中的一员,其受体Gas6和Mer结合后可以激活Mer的酪氨酸激酶活性,并激活下游信号传导途径,在细胞炎症、凋亡、血液肿瘤发生发展以及血栓于止血等方面发挥作用。
3.
FLT3,a member of receptor tyrosine kinase III family,is primarily expressed by hematopoietic cells and plays a significant role in hematopoiesis and leukemogenesis.
FMS-like Tyrosine Kinase 3(FLT3)是一种受体酪氨酸激酶,在造血干细胞、前体B细胞等的增殖、分化以及存活中具有重要作用。
补充资料：酪氨酸蛋白激酶抑制剂
分子式：
CAS号：
性质：一类能抑制蛋白质酪氨酸激酶活性的化合物。酪氨酸蛋白激酶能特异性地将磷酸根转移到蛋白质的酪氨酸残基上使其磷酸化，是许多配体活化的生长因子受体和一些癌基因产物，在肿瘤组织中含量高。酪氨酸蛋白激酶抑制剂可作为ATP与酪氨酸蛋白激酶结合的竞争性抑制剂，也可作为酪氨酸的类似物阻断表皮生长因子受体的肽位点和酪氨酸蛋白激酶的编码，抑制细胞增殖，可望开发为抗肿瘤药物，但对完整细胞没有表现出选择性。
CAS号：
性质：一类能抑制蛋白质酪氨酸激酶活性的化合物。酪氨酸蛋白激酶能特异性地将磷酸根转移到蛋白质的酪氨酸残基上使其磷酸化，是许多配体活化的生长因子受体和一些癌基因产物，在肿瘤组织中含量高。酪氨酸蛋白激酶抑制剂可作为ATP与酪氨酸蛋白激酶结合的竞争性抑制剂，也可作为酪氨酸的类似物阻断表皮生长因子受体的肽位点和酪氨酸蛋白激酶的编码，抑制细胞增殖，可望开发为抗肿瘤药物，但对完整细胞没有表现出选择性。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条