1) enantioselective reduction
噻唑烷并手性噁唑硼烷
1.
Quantum chemical study on enantioselective reduction of aromatic ketones catalyzed by chiral thiazolidino [3,4-c] oxazaborolidine;
噻唑烷并手性噁唑硼烷催化芳香酮的不对称还原反应的量子化学研究
2) chiral oxazaborolidine
手性噁唑硼烷
1.
The asymmetric reduction of 3-chloropropiophenone catalyzed by chiral oxazaborolidines enantioselectively gave S- or R-3-chloro-1-phenylpropanol (2) in good yield.
以自制的手性噁唑硼烷为催化剂,将起始原料β-氯苯丙酮不对称催化氢化还原成(S)-或(R)-手性醇,这一步的化学收率和光学收率都较高。
2.
The asymmetric reduction of ethyl γ-chloroacetoacetate catalyzed by chiral oxazaborolidines enantioselectively gave ethyl R-3-hydroxy-4-chlorobutyrate in good yield and enantioselectivity.
以自制的手性噁唑硼烷为催化剂,将起始原料γ-氯乙酰乙酸乙酯不对称催化氢化还原成(R)-γ-氯-β-羟基丁酸乙酯,这一步的化学收率和光学收率都较高。
3.
The formed chiral oxazaborolidines in situ have been used in the enantioselective borane reduction of prochiral ketones affording the alcohol products with enantiomeric excesses (ee) up to 96%.
首次以天然D-樟脑的衍生物为原料,合成了两个新型龙脑基氨基醇配体,研究了它们与硼烷原位制备成手性噁唑硼烷后,在不对称催化氢化还原前手性芳酮中的性能,得到的手性仲醇的对映体过量(ee)值最高可达96%,还考察了反应温度、时间、溶剂等因素对苯乙酮的不对称氢化还原的化学产率和光学收率的影响。
3) chiral thiazolidino [3,4 c] oxazaborolidine
噻唑烷并手性口恶唑硼烷
4) oxazaborolidine
噁唑硼烷
1.
The asymmetric reduction of ketosulfone with borane catalyzed by oxazaborolidine is computed by means of the semi-empirical MNDO method.
对噁唑硼烷催化前手性酮砜不对称还原反应进行了半经验MNDO研究。
2.
Asymmetric reduction of prochiral ketones using oxazaborolidines has become one of the standard tools for the synthetic chemist, allowing access to enantiomerically enriched secondary alcohols with excellent enantiomeric excess that may seve as the chiral ligands for enantionselectivity synthesis and highly useful intermediates in the sy.
手性噁唑硼烷催化前手性酮的不对称还原反应已成为合成化学家的重要手段之一,这种方法获得的手性仲醇具有较高的ee 值,它们可作为不对称合成中的手性配体及活性物质、天然产物和药物的手性中间体。
5) chiral sulfu containing oxazaborolidine
手性含硫噁唑硼烷
6) chiral pyrrolidino oxazaborolidine
吡咯烷并手性唑硼烷
1.
In this paper, the semi empirical AM1 molecular orbital method is used to study the enantioselective reduction of aromatic ketone catalyzed by chiral pyrrolidino oxazaborolidine without model substituents.
在不用模型分子的条件下 ,用量子化学半经验 AM1方法研究了吡咯烷并手性唑硼烷催化芳香酮的不对称还原反应机理。
补充资料：癸硼烷
化学式B10H14。 常温下为固体； 熔点99.5℃，沸点213℃；为最稳定的硼烷,不自燃,在无空气存在下,加热至150℃也不分解。 癸硼烷可用作橡胶的硫化剂和乙烯聚合的催化剂。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条