1) Rofecoxib derivatives
罗非昔布开环衍生物
2) derivatives of rofecoxib
罗非昔布衍生物
3) Refecoxib
罗非昔布
1.
Evidence-Based Safety Reassessment of Post Marketed Drug — Importance of Recall of Refecoxib;
应重视上市后药物安全性的循证医学再评价——罗非昔布召回的意义
2.
A clinical study of Refecoxib and antibiotics for treatment of chronic prostatitis;
罗非昔布联合抗生素治疗慢性前列腺炎
4) rofecoxib
罗非昔布
1.
Analysis of withdrawal of rofecoxib-cyclooxygenase-2 specific inhibitor;
高选择性COX-2抑制剂罗非昔布撤市分析
2.
Effect of selective cyclooxygenase-2 inhibitor rofecoxib on the growth of human carcinoma of gallbladder;
选择性环氧合酶-2抑制剂罗非昔布对胆囊癌生长的影响
3.
Effect of rofecoxib on expressions of VEGF and inducible NOS in human gastric carcinoma tissues established in nude mice by orthotopic transplantation;
罗非昔布对裸鼠人胃癌原位种植瘤组织中血管内皮生长因子和诱导型一氧化氮合酶表达的影响
5) open ring derivatives
开环衍生物
1.
In this thesis,a type of cordalis alkaloid corydaline,which has demonstrated moderate inhibition to ACHE,was used as a lead compound to obtain the action mechanism of corydaline to ACHE and screen a series of its open ring derivatives by means of molecular docking and virtual screen.
本文以具有中等AChE抑制活性的延胡索类生物碱corydaline为先导化合物,研究了它与AChE的相互作用模式,引入开环与增长碳链长的思想,虚拟筛选获得了一系列具有潜在高活性的开环衍生物;对预测活性较高的4个开环衍生物(Ⅰ_1～Ⅰ_4)进行了合成研究与结构表征;并对目标产物Ⅰ_1～Ⅰ_4与关键中间体Ⅵ_1～Ⅵ_4进行了体外AChE抑制活性测定及药代动力学与毒性(ADMET)预测。
6) Piroxicam/analogs & derivatives
吡罗昔康/类似物和衍生物
补充资料：罗非昔布
分子式：C17H14O4S
分子量：314.35
CAS号：162011-90-7
性质：熔点207°C。
分子量：314.35
CAS号：162011-90-7
性质：熔点207°C。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条